Investigation of the Relationship Between Health Literacy and Adherence to Immunosuppressive Therapy in Heart Transplant Patients: A Cross-Sectional Study

IF 0.8 4区 医学 Q4 IMMUNOLOGY Transplantation proceedings Pub Date : 2025-11-01 Epub Date: 2025-03-17 DOI:10.1016/j.transproceed.2025.01.008
Nihal Celikturk Doruker , Tugba Nur Oden , Fatma Demir Korkmaz
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Abstract

Background

Nonadherence to immunosuppressive therapy after heart transplantation, driven by factors such as patient, caregiver, institutional, policy-related issues, and health literacy, leads to rejection and increased mortality. This study aimed to investigate the relationship between health literacy and adherence to immunosuppressive therapy in heart transplant patients.

Methods

The sample of this cross-sectional study consisted of 57 patients who underwent heart transplantation in a university hospital in Izmir, Turkey. “Sociodemographic and Descriptive Characteristics Form”, “Data on Immunosuppressive Drug Therapy Form”, “Rapid Estimate of Adult Health Literacy in Medicine (REALM) Scale”, and “Immunosuppressive Therapy Adherence Scale (ITAS)” were used to collect the data..

Results

The median score on the REALM scale was 64.00 (IQR = 3.00, min = 18.00, max = 66.00) and 80.7% of the patients scored adequately. The median score of the immunosuppressive therapy adherence scale was 11.00 (IQR= 1.00, min= 5.00, max= 12.00) and 42.1% of the patients scored full score. There was no statistically significant relationship between the median total scores of the REALM and ITAS scales in heart transplant patients (r = 0.181, P = .178).

Conclusions

In this study, the majority of heart transplant patients had adequate health literacy. It was found that less than half of these patients adhered to immunosuppressive therapy. Less than half of these patients were found to comply with immunosuppressive therapy. In this study, no relationship was found between health literacy and adherence to immunosuppressive therapy.
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心脏移植患者健康素养与免疫抑制治疗依从性关系的横断面研究
背景:心脏移植后不坚持免疫抑制治疗,由患者、护理人员、机构、政策相关问题和健康素养等因素驱动,导致排斥反应和死亡率增加。本研究旨在探讨心脏移植患者健康素养与免疫抑制治疗依从性之间的关系。方法:本横断面研究的样本包括在土耳其伊兹密尔一所大学医院接受心脏移植的57例患者。采用《社会人口统计学及描述性特征表》、《免疫抑制药物治疗资料表》、《成人医学健康素养快速评估量表(REALM)》和《免疫抑制药物治疗依从性量表(ITAS)》收集资料。结果:REALM量表中位数为64.00分(IQR = 3.00, min = 18.00, max = 66.00), 80.7%的患者得分充分。免疫抑制治疗依从性量表中位得分为11.00 (IQR= 1.00, min= 5.00, max= 12.00), 42.1%的患者获得满分。心脏移植患者REALM总分和ITAS总分中位数之间无统计学意义(r = 0.181, P = 0.178)。结论:在本研究中,大多数心脏移植患者具有足够的健康素养。发现这些患者中只有不到一半坚持免疫抑制治疗。这些患者中只有不到一半的人接受了免疫抑制治疗。在这项研究中,没有发现健康素养和免疫抑制治疗依从性之间的关系。
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来源期刊
Transplantation proceedings
Transplantation proceedings 医学-免疫学
CiteScore
1.70
自引率
0.00%
发文量
502
审稿时长
60 days
期刊介绍: Transplantation Proceedings publishes several different categories of manuscripts, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. The first type of manuscripts consists of sets of papers providing an in-depth expression of the current state of the art in various rapidly developing components of world transplantation biology and medicine. These manuscripts emanate from congresses of the affiliated transplantation societies, from Symposia sponsored by the Societies, as well as special Conferences and Workshops covering related topics. Transplantation Proceedings also publishes several special sections including publication of Clinical Transplantation Proceedings, being rapid original contributions of preclinical and clinical experiences. These manuscripts undergo review by members of the Editorial Board. Original basic or clinical science articles, clinical trials and case studies can be submitted to the journal?s open access companion title Transplantation Reports.
期刊最新文献
Editorial Board Contents Author Index Simultaneous Heart-Liver Transplant Using Dual-Organ Normothermic Machine Perfusion Following Donation After Circulatory Death: A Case Report A Case of Transplant Kidney Infected Hydronephrosis Complicated by Pyonephrosis 15 Years Post-Transplantation: A Case Report and Literature Review
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