{"title":"Digital pathways connecting social and biological factors to health outcomes and equity","authors":"Yan Cui","doi":"10.1038/s41746-025-01564-8","DOIUrl":null,"url":null,"abstract":"Digital pathways extend conventional connections between social and biological factors and health outcomes, significantly influencing health equity. Data representation bias and distribution shifts are key mechanisms through which determinants of health impact generalizability of artificial intelligence (AI) models and subsequently affect health outcomes and equity. These mechanisms provide critical targets for algorithmic interventions, which can lead to Pareto improvements in AI model performance across diverse populations, thereby mitigating health disparities.","PeriodicalId":19349,"journal":{"name":"NPJ Digital Medicine","volume":"44 1","pages":""},"PeriodicalIF":12.4000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"NPJ Digital Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41746-025-01564-8","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Digital pathways extend conventional connections between social and biological factors and health outcomes, significantly influencing health equity. Data representation bias and distribution shifts are key mechanisms through which determinants of health impact generalizability of artificial intelligence (AI) models and subsequently affect health outcomes and equity. These mechanisms provide critical targets for algorithmic interventions, which can lead to Pareto improvements in AI model performance across diverse populations, thereby mitigating health disparities.
期刊介绍：
npj Digital Medicine is an online open-access journal that focuses on publishing peer-reviewed research in the field of digital medicine. The journal covers various aspects of digital medicine, including the application and implementation of digital and mobile technologies in clinical settings, virtual healthcare, and the use of artificial intelligence and informatics.
The primary goal of the journal is to support innovation and the advancement of healthcare through the integration of new digital and mobile technologies. When determining if a manuscript is suitable for publication, the journal considers four important criteria: novelty, clinical relevance, scientific rigor, and digital innovation.
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