Mohammad Alhomoud, Ali Alshehri, Hazzaa A. Alzahrani
{"title":"Enlargement of Shoulder Muscles in an Older Man","authors":"Mohammad Alhomoud, Ali Alshehri, Hazzaa A. Alzahrani","doi":"10.1001/jamaoncol.2025.0071","DOIUrl":null,"url":null,"abstract":"A 70-year-old man with a history of hypertension and chronic migraine presented with 10 months of progressive generalized muscle weakness and stiffness. Physical examination revealed generalized muscle wasting except for hypertrophy of bilateral shoulder muscles, and a deltoid muscle biopsy revealed deposition of amorphous material. What is your diagnosis?","PeriodicalId":14850,"journal":{"name":"JAMA Oncology","volume":"92 1","pages":""},"PeriodicalIF":22.5000,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JAMA Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1001/jamaoncol.2025.0071","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
A 70-year-old man with a history of hypertension and chronic migraine presented with 10 months of progressive generalized muscle weakness and stiffness. Physical examination revealed generalized muscle wasting except for hypertrophy of bilateral shoulder muscles, and a deltoid muscle biopsy revealed deposition of amorphous material. What is your diagnosis?
期刊介绍:
JAMA Oncology is an international peer-reviewed journal that serves as the leading publication for scientists, clinicians, and trainees working in the field of oncology. It is part of the JAMA Network, a collection of peer-reviewed medical and specialty publications.