Evolution and innovation in urethroplasty: a comprehensive narrative review of graft types and surgical techniques.

IF 2.5 3区 医学 Q2 UROLOGY & NEPHROLOGY International Journal of Impotence Research Pub Date : 2025-03-19 DOI:10.1038/s41443-025-01040-7
Donato Cannoletta, Filippo Pederzoli, Christian Yepes, Pankaj Joshi, Andrea Salonia, Alberto Briganti, Francesco Montorsi, Sanjay Kulkarni, Marco Bandini
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Abstract

Urethroplasty has evolved over last decades, with significant improvements in surgical techniques and graft types. In this narrative review, we aimed to explore the evolution of urethroplasty techniques for bulbar urethral strictures. To do this, the review is structured into three main sections: the Historical Background section highlights the seminal contribution from early pioneers to contemporary techniques, which re-gained momentum in reconstructive urology. Starting with the early techniques in the 19th and 20th centuries, we focused on the pioneering innovations of the 1990s, ultimately leading to the most recent tissue-preserving techniques. The second part presents a literature review comparing different graft types and critically evaluating surgical outcomes from multiple original articles and meta-analysis. Specifically, similar success rates were reported for oral and preputial grafts for the treatment of anterior urethral strictures, while long-term outcomes suggest graft deterioration over time. Furthermore, data on optimal surgical techniques remain limited. Lastly, Future Perspectives address ongoing innovations, including new graft and flap combinations for complex strictures, emphasizing the continuous refinement of less invasive, tissue-preserving techniques.

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尿道成形术的发展与创新:移植物类型和手术技术的综合综述。
在过去的几十年里,随着手术技术和移植类型的显著改进,尿道成形术得到了发展。在这篇叙述性的综述中,我们旨在探讨尿道成形术治疗球尿道狭窄技术的发展。为此,本综述分为三个主要部分:历史背景部分强调了早期先驱对当代技术的开创性贡献,这些技术在泌尿外科重建中重新获得了动力。从19世纪和20世纪的早期技术开始,我们专注于20世纪90年代的开创性创新,最终导致最新的组织保存技术。第二部分介绍了文献综述,比较了不同的移植物类型,并从多个原始文章和荟萃分析中批判性地评估了手术结果。具体来说,口腔和包皮移植治疗前尿道狭窄的成功率相似,但长期结果表明移植物会随着时间的推移而恶化。此外,关于最佳手术技术的数据仍然有限。最后,《未来展望》讨论了正在进行的创新,包括用于复杂狭窄的新型移植物和皮瓣组合,强调了微创、组织保存技术的不断完善。
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来源期刊
International Journal of Impotence Research
International Journal of Impotence Research 医学-泌尿学与肾脏学
CiteScore
4.90
自引率
19.20%
发文量
140
审稿时长
>12 weeks
期刊介绍: International Journal of Impotence Research: The Journal of Sexual Medicine addresses sexual medicine for both genders as an interdisciplinary field. This includes basic science researchers, urologists, endocrinologists, cardiologists, family practitioners, gynecologists, internists, neurologists, psychiatrists, psychologists, radiologists and other health care clinicians.
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