Non-anatomical revascularization of the portal vein in children with non-cirrhotic extrahepatic portal vein obstruction.

IF 2.3 3区 医学 Q2 PEDIATRICS Pediatric Radiology Pub Date : 2025-05-01 Epub Date: 2025-03-19 DOI:10.1007/s00247-025-06218-1
Kessy Djonis Martins de Mattos, Paolo Marra, Francesco Saverio Carbone, Riccardo Muglia, Ludovico Dulcetta, Stefano Fagiuoli, Lorenzo D'Antiga, Sandro Sironi
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Abstract

Portal hypertension resulting from non-cirrhotic extrahepatic portal vein obstruction is a cause of severe morbidity related to variceal bleeding in children. In patients not eligible for Meso-Rex bypass, rescue interventions for refractory variceal bleeding have traditionally included surgical porto-systemic shunts or transjugular intrahepatic porto-systemic shunt (TIPS), which alter the normal physiology of liver perfusion and expose children to long-term complications. Portal vein recanalization is a recently described technique which aims to restore the hepatopetal flow through the native portal system but its feasibility is often limited. We aim to present two innovative techniques of percutaneous non-anatomical portal vein recanalization for treating non-cirrhotic extrahepatic portal vein obstruction in children who failed anatomical revascularization.

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非肝硬化肝外门静脉梗阻患儿门静脉非解剖性血运重建术。
由非肝硬化肝外门静脉阻塞引起的门静脉高压是儿童静脉曲张出血的严重并发症。对于不适合Meso-Rex搭桥的患者,难治性静脉曲张出血的抢救干预传统上包括手术门静脉-全身分流术或经颈静脉肝内门静脉-全身分流术(TIPS),这改变了肝脏灌注的正常生理,使儿童暴露于长期并发症。门静脉再通术是一种旨在通过原生门静脉系统恢复肝壁血流的新技术,但其可行性往往受到限制。我们的目的是提出两种创新的经皮非解剖性门静脉再通技术,用于治疗解剖性血流重建术失败的儿童非肝硬化肝外门静脉阻塞。
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来源期刊
Pediatric Radiology
Pediatric Radiology 医学-核医学
CiteScore
4.40
自引率
17.40%
发文量
300
审稿时长
3-6 weeks
期刊介绍: Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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