Taufiek Konrad Rajab, David M Kalfa, Carlos Mery, Sitaram M Emani, Brian L Reemtsen
{"title":"Indications and Practical Considerations for Partial Heart Transplantation.","authors":"Taufiek Konrad Rajab, David M Kalfa, Carlos Mery, Sitaram M Emani, Brian L Reemtsen","doi":"10.1016/j.athoracsur.2025.01.037","DOIUrl":null,"url":null,"abstract":"<p><p>Partial heart transplantation is a new approach to deliver growing heart valve substitutes. The rationale for partial heart transplantation is that the valves contained in heart transplants grow. Partial heart transplants differ from heart transplants because only the part of the heart containing the necessary valve is transplanted, while the native ventricles are preserved. Preserving the native ventricles eliminates the risk of graft ventricular dysfunction and allows for utilization of donor hearts with ventricular dysfunction. Here we outline practical considerations for partial heart transplantation, including indications, institutional oversight, sources for donor hearts, graft procurement, graft preservation, implantation, recipient immunosuppression, and reimbursement. This invited expert review is intended to help clinical teams implement partial heart transplantation.</p>","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":" ","pages":""},"PeriodicalIF":3.6000,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Thoracic Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.athoracsur.2025.01.037","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Partial heart transplantation is a new approach to deliver growing heart valve substitutes. The rationale for partial heart transplantation is that the valves contained in heart transplants grow. Partial heart transplants differ from heart transplants because only the part of the heart containing the necessary valve is transplanted, while the native ventricles are preserved. Preserving the native ventricles eliminates the risk of graft ventricular dysfunction and allows for utilization of donor hearts with ventricular dysfunction. Here we outline practical considerations for partial heart transplantation, including indications, institutional oversight, sources for donor hearts, graft procurement, graft preservation, implantation, recipient immunosuppression, and reimbursement. This invited expert review is intended to help clinical teams implement partial heart transplantation.
期刊介绍:
The mission of The Annals of Thoracic Surgery is to promote scholarship in cardiothoracic surgery patient care, clinical practice, research, education, and policy. As the official journal of two of the largest American associations in its specialty, this leading monthly enjoys outstanding editorial leadership and maintains rigorous selection standards.
The Annals of Thoracic Surgery features:
• Full-length original articles on clinical advances, current surgical methods, and controversial topics and techniques
• New Technology articles
• Case reports
• "How-to-do-it" features
• Reviews of current literature
• Supplements on symposia
• Commentary pieces and correspondence
• CME
• Online-only case reports, "how-to-do-its", and images in cardiothoracic surgery.
An authoritative, clinically oriented, comprehensive resource, The Annals of Thoracic Surgery is committed to providing a place for all thoracic surgeons to relate experiences which will help improve patient care.