Meta-analysis of high-intensity interval training effects on cognitive function in older adults and cognitively impaired patients.

IF 3.2 3区医学 Q2 PHYSIOLOGY Frontiers in Physiology Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI:10.3389/fphys.2025.1543217

Wenting Zhang, Shuyi Zeng, Yao Nie, Keke Xu, Qiyuan Zhang, Yu Qiu, Yongqiang Li

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Abstract

Background: Cognitive enhancement treatments are limited, and while High-Intensity Interval Training (HIIT) has been suggested to improve cognitive function, high-quality evidence remains scarce. This meta-analysis evaluates the effects of HIIT on cognitive performance compared to moderate-intensity continuous training (MICT) and control groups in older adults and cognitively Impaired Patients.

Methods: A systematic search of PubMed, Embase, and Cochrane Library databases was conducted for articles published until 10 October 2024. Eighteen studies were included, comparing cognitive outcomes across HIIT, MICT, and control groups. Cognitive tests evaluated included the Stroop test, Digit Span Test (DST), Trail Making Test (TMT), and the MOST test.

Results: HIIT significantly improved performance compared to MICT in the Stroop test (SMD = -0.8, 95% CI: -1.3 to -0.2) and DST (SMD = 0.3, 95% CI: -0.0-0.5). Compared to control groups, HIIT significantly enhanced performance in the TMT (SMD = -0.7, 95% CI: -1.3 to 0.0) and MOST test (SMD = -1.2, 95% CI: -1.8 to -0.7).

Conclusion: This meta-analysis supports the efficacy of HIIT in enhancing cognitive functions, particularly in cognitive flexibility, working memory, task switching, attention control, and inhibitory control. These findings suggest that HIIT can be an effective intervention for improving cognitive behavior in older adults and cognitively Impaired Patients.

Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/, Identifier CRD42023413879.

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高强度间歇训练对老年人和认知障碍患者认知功能影响的meta分析。

背景：虽然高强度间歇训练（HIIT）被认为可以改善认知功能，但高质量的证据仍然很少。本荟萃分析评估了高强度间歇训练与中强度持续训练（MICT）和对照组相比对老年人和认知障碍患者认知能力的影响：对 PubMed、Embase 和 Cochrane 图书馆数据库中截至 2024 年 10 月 10 日发表的文章进行了系统检索。共纳入 18 项研究，比较了 HIIT、MICT 和对照组的认知结果。评估的认知测试包括 Stroop 测试、数字跨度测试 (DST)、寻迹测试 (TMT) 和 MOST 测试：结果：在 Stroop 测试（SMD = -0.8，95% CI：-1.3 至 -0.2）和 DST 测试（SMD = 0.3，95% CI：-0.0-0.5）中，HIIT 比 MICT 明显提高了成绩。与对照组相比，HIIT 能显著提高 TMT（SMD = -0.7，95% CI：-1.3 至 0.0）和 MOST 测试（SMD =-1.2，95% CI：-1.8 至 -0.7）的成绩：这项荟萃分析支持 HIIT 在增强认知功能方面的功效，尤其是在认知灵活性、工作记忆、任务转换、注意力控制和抑制控制方面。这些研究结果表明，HIIT 是改善老年人和认知障碍患者认知行为的有效干预措施。系统综述注册：https://www.crd.york.ac.uk/PROSPERO/，标识符为 CRD42023413879。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Physiology PHYSIOLOGY-

CiteScore

6.50

自引率

5.00%

发文量

2608

审稿时长

14 weeks

期刊介绍： Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.