Insight into the lifestyle of young people with chronic liver disease.

IF 2.6 3区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2025-06-01 Epub Date: 2025-03-21 DOI:10.1002/jpn3.70030
Mohamed Ali, Sowmiya Gunabalasingam, Jemma Day, Jenny Yerlett, Lisa Clay, Paul Mckie, Sophie Cant, Alison Taylor, Jeremy Nayagam, Deepak Joshi, Grainne McAlonan, Marianne Samyn
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Abstract

The impact of chronic liver disease (CLD) in young people on lifestyle is poorly explored. One hundred four young people (20.51 years, male 44%), including 37% with autoimmune liver disease and 19% post-liver transplantation, completed an anonymous health questionnaire Thirty-nine per cent were considered overweight/obese. Female body mass index (BMI) was higher than male BMI (26.5 vs. 23.4, p = 0.018), and those taking steroids (n = 38) were more likely to be overweight/obese (66% vs. 31%, p = 0.03). Half of the cohort reported 'never' to drink alcohol and 19% had taken recreational drugs with 5% mentioning regular use of alcohol and recreational drugs each. Menstrual dysregulation was common including oligomenorrhoea (31%) and irregular periods (25%). The prevalence of overweight/obese status in young people with CLD is worrying, with females and those on steroid treatment most affected. Whereas alcohol consumption is less common compared to peers, the use of recreational drugs in this population warrants further attention.

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了解慢性肝病年轻人的生活方式。
年轻人慢性肝病(CLD)对生活方式的影响尚不清楚。104名年轻人(20.51岁,男性44%)完成了一份匿名健康问卷,其中37%患有自身免疫性肝病,19%接受肝移植。39%的人被认为超重/肥胖。女性身体质量指数(BMI)高于男性(26.5比23.4,p = 0.018),服用类固醇(n = 38)的人更容易超重/肥胖(66%比31%,p = 0.03)。一半的人报告说“从不”喝酒,19%的人服用消遣性药物,5%的人提到经常使用酒精和消遣性药物。月经失调很常见,包括少经(31%)和月经不规律(25%)。年轻CLD患者中超重/肥胖的患病率令人担忧,女性和接受类固醇治疗的人群受影响最大。尽管与同龄人相比,饮酒不太常见,但这一人群中娱乐性药物的使用值得进一步关注。
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来源期刊
CiteScore
5.30
自引率
13.80%
发文量
467
审稿时长
3-6 weeks
期刊介绍: ​The Journal of Pediatric Gastroenterology and Nutrition (JPGN) provides a forum for original papers and reviews dealing with pediatric gastroenterology and nutrition, including normal and abnormal functions of the alimentary tract and its associated organs, including the salivary glands, pancreas, gallbladder, and liver. Particular emphasis is on development and its relation to infant and childhood nutrition.
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