Bromotrifluoromethoxylation of allenes: expedient access to allylic trifluoromethoxy derivatives†

Abstract

A mild and efficient method for the bromotrifluoromethoxylation of allenes has been explored using trifluoromethyl arylsulfonate (TFMS) as the trifluoromethoxy source. A series of allylic trifluoromethoxy derivatives were obtained with high yields and good regioselectivity by terminal selectivity of the allenes. This transition metal-free process expands the scope of the application of trifluoromethoxy reagents.