{"title":"Bromotrifluoromethoxylation of Allenes: An Expedient Access to Allylic Trifluoromethoxy Derivatives","authors":"Rui Liu, Yangdong Hou, Pingping Tang","doi":"10.1039/d4qo02426e","DOIUrl":null,"url":null,"abstract":"A mild and efficient method for bromotrifluoromethoxylation of allenes was explored using trifluoromethyl arylsulfonate (TFMS) as the trifluoromethoxy source. A series of allylic trifluoromethoxy derivatives were obtained with high yields and good regioselectivity by terminal selectivity of allenes. This transition metal-free process expanded the scope of the application of trifluoromethoxy reagent.","PeriodicalId":97,"journal":{"name":"Organic Chemistry Frontiers","volume":"34 1","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic Chemistry Frontiers","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4qo02426e","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A mild and efficient method for bromotrifluoromethoxylation of allenes was explored using trifluoromethyl arylsulfonate (TFMS) as the trifluoromethoxy source. A series of allylic trifluoromethoxy derivatives were obtained with high yields and good regioselectivity by terminal selectivity of allenes. This transition metal-free process expanded the scope of the application of trifluoromethoxy reagent.
期刊介绍：
Organic Chemistry Frontiers is an esteemed journal that publishes high-quality research across the field of organic chemistry. It places a significant emphasis on studies that contribute substantially to the field by introducing new or significantly improved protocols and methodologies. The journal covers a wide array of topics which include, but are not limited to, organic synthesis, the development of synthetic methodologies, catalysis, natural products, functional organic materials, supramolecular and macromolecular chemistry, as well as physical and computational organic chemistry.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
