Glycemia Assessed by Continuous Glucose Monitoring among People Treated with Maintenance Dialysis.

IF 9.4 1区 医学 Q1 UROLOGY & NEPHROLOGY Journal of The American Society of Nephrology Pub Date : 2025-03-21 DOI:10.1681/ASN.0000000693
Ian H de Boer, Lisa D Anderson, Nathaniel K Ashford, Ernest Ayers, Nisha Bansal, Yoshio N Hall, Irl B Hirsch, Andrew N Hoofnagle, Simon Hsu, Evelin Jones, Benjamin Lidgard, Christine P Limonte, Lori J Linke, Chris C Marnell, Laura Mayeda, Elizabeth McNamara, Rajnish Mehrotra, Anne Pesenson, Julie M Porter, Matthew B Rivara, Glenda V Roberts, Beth Shanaman, Subbulaxmi Trikudanathan, Suzanne Watnick, Katy G Wilkens, Leila R Zelnick
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通过连续血糖监测评估维持性透析患者的血糖水平。
背景:肾衰竭及其治疗方法会破坏葡萄糖稳态,从而导致高血糖和低血糖。连续血糖监测(CGM)可勾勒出详细的血糖曲线,但已发表的肾衰竭研究仅限于少数特定人群。我们的目标是描述一个庞大、多样化的维持性透析人群的血糖谱及其决定因素:我们对接受维持性透析治疗的人群进行了一项基于社区的前瞻性队列研究。每位参与者佩戴 Dexcom G6 Pro CGM 约 10 天。CGM 确定的结果包括平均血糖、在量程内的时间(TIR,70-180 mg/dL)和低血糖事件(持续结果):我们招募了 420 名不同人群的参与者,包括 263 名糖尿病患者(其中 88 人未经降糖药物治疗)和 157 名非糖尿病患者。55人使用腹膜透析。结果因糖尿病状况和透析方式而异。在无糖尿病的参与者中,腹膜透析与血液透析相比,平均血糖更高(141 vs 121 mg/dL,p结论:在维持性透析中,血糖监测仪经常会发现临床上可能并不明显的高血糖和低血糖。特别是,腹膜透析中常见高血糖,未经治疗的糖尿病患者会维持糖尿病血糖状况,而经过治疗的糖尿病患者很少能达到基于 CGM 的现代治疗目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of The American Society of Nephrology
Journal of The American Society of Nephrology 医学-泌尿学与肾脏学
CiteScore
22.40
自引率
2.90%
发文量
492
审稿时长
3-8 weeks
期刊介绍: The Journal of the American Society of Nephrology (JASN) stands as the preeminent kidney journal globally, offering an exceptional synthesis of cutting-edge basic research, clinical epidemiology, meta-analysis, and relevant editorial content. Representing a comprehensive resource, JASN encompasses clinical research, editorials distilling key findings, perspectives, and timely reviews. Editorials are skillfully crafted to elucidate the essential insights of the parent article, while JASN actively encourages the submission of Letters to the Editor discussing recently published articles. The reviews featured in JASN are consistently erudite and comprehensive, providing thorough coverage of respective fields. Since its inception in July 1990, JASN has been a monthly publication. JASN publishes original research reports and editorial content across a spectrum of basic and clinical science relevant to the broad discipline of nephrology. Topics covered include renal cell biology, developmental biology of the kidney, genetics of kidney disease, cell and transport physiology, hemodynamics and vascular regulation, mechanisms of blood pressure regulation, renal immunology, kidney pathology, pathophysiology of kidney diseases, nephrolithiasis, clinical nephrology (including dialysis and transplantation), and hypertension. Furthermore, articles addressing healthcare policy and care delivery issues relevant to nephrology are warmly welcomed.
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