Gender specific echocardiographic prevalence of valvular stenosis and regurgitations in a large inpatient database of 24,265 patients.

Abstract

Introduction: Prevalence of different valvular pathologies has not been reported in female and male patients in large population-based studies. The goal of this study was to report the gender-specific prevalence of various valvular pathologies.

Methods: We retrospectively analyzed 24,265 echocardiograms performed between 1984 and 1998. The prevalence of mitral regurgitation (MR) aortic valve regurgitation (AR) and stenosis (AS), and tricuspid regurgitation (TR) were calculated in female and male patients.

Results: Echocardiograms were performed on 12,926 (53%) female and 11,339 (47%) male patients. Gender-specific echocardiographic prevalence of different valvular abnormalities was as follows: Prevalence of mitral regurgitations was similar in women and men (25% vs 24.7%). Aortic regurgitation was higher in males (5.5 vs 14.9%, P < 0.001). Aortic stenosis prevalence was similar between both genders (2.1 vs 2.3%). Tricuspid valve regurgitations were slightly higher in females (18.5 vs 16.7%, P < 0.001).

Conclusion: In this study, we found a significantly higher prevalence of tricuspid valve regurgitation in women. Aortic regurgitation was more prevalent in men. Aortic stenosis and mitral regurgitation had similar prevalence in both genders.