Vaccines reimagined: The peptide revolution in disease prevention.

Abstract

Peptide-based vaccines have emerged as a promising avenue in the realm of immunization strategies. This chapter provides an overview of the key aspects and advancements in peptide-based vaccine development. Peptides, as fragments of larger proteins, hold the potential to induce targeted immune responses while minimizing off-target effects. We discuss the principles of peptide selection, epitope identification, and delivery platforms, underscoring the importance of rational design to optimize immunogenicity. The integration of computational tools and advanced analytical methods has enabled the refinement of peptide vaccine candidates. Studies on infectious diseases, cancers, and new pathogens showcase the versatility and efficacy of peptide vaccines. As the field progresses, collaborative efforts between researchers, industry, and healthcare systems are essential to bridge the gap from laboratory research to clinical application. The future holds promise for peptide-based vaccines to contribute significantly to disease prevention and therapeutic intervention.