The Excess Mortality Among Twins in the Dominican Republic and Haiti Through the Components of Age Under Five: A Comparative Study of Trends and Associated Factors.

IF 1.2 4区 医学 Q4 GENETICS & HEREDITY Twin Research and Human Genetics Pub Date : 2025-03-24 DOI:10.1017/thg.2025.11
Adama Ouedraogo, David Jean Simon, Ann Kiragu, Nicole Estefany Aponte Cueto, Vénunyé Claude Kondo Tokpovi
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Abstract

Despite the decline in mortality rates among children in developing countries, disparities persist between countries, particularly between twins and singletons. This study employed data from nine Demographic and Health Surveys in the Dominican Republic and Haiti to estimate and compare mortality rates for twins and singletons in categories of the under-5 age group (neonatal, postneonatal, and child mortality) and examine the factors associated with excess mortality among twins. From 1996 to 2013, the under-5 mortality rate (U5MR) for singletons in the Dominican Republic declined from 56‰ (95% CI [47, 64) to 30‰ (22-39) and from 108‰ (53-164) to 53‰ (16-89) among twins. In Haiti, between 1994 and 2016, the U5MR declined from 121‰ (109-133) to 77‰ (68-80) for singletons and from 432‰ (327-538) to 204‰ (149-260) among twins. The adjusted risk of neonatal death for twins is 1.4 (1.0-1.9) times higher than for singletons in the Dominican Republic, compared to a risk of 4.3 (3.5-5.3) times higher in Haiti. In the post-neonatal period, the mortality risk for twins in the Dominican Republic was 1.8 (1.0-3.1) times higher than that for singletons, 2.9 (2.3-3.8) in Haiti. The risk of death for twins was not significantly different from that for singletons in both the Dominican Republic and Haiti at ages 1-4 years. Low birth weight, lack of breastfeeding, absence of, or inadequate, antenatal care, noncesarean section birth, and high birth order were associated with excess mortality among twins in both countries.

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多明尼加共和国和海地五岁以下双胞胎的超额死亡率:趋势和相关因素的比较研究。
尽管发展中国家的儿童死亡率有所下降,但国家之间的差距仍然存在,特别是双胞胎和单胎之间的差距。本研究采用了多米尼加共和国和海地9项人口与健康调查的数据,以估计和比较5岁以下年龄组(新生儿、新生儿后期和儿童死亡率)双胞胎和单胎婴儿的死亡率,并检查与双胞胎死亡率过高相关的因素。1996年至2013年,多米尼加共和国单胎5岁以下儿童死亡率(U5MR)从56‰(95% CI[47, 64])下降到30‰(22-39),双胞胎从108‰(53-164)下降到53‰(16-89)。在海地,1994年至2016年期间,单胎的U5MR从121‰(109-133)下降到77‰(68-80),双胞胎的U5MR从432‰(327-538)下降到204‰(149-260)。在多米尼加共和国,双胞胎新生儿死亡的调整后风险是单胎新生儿死亡的1.4倍(1.0-1.9),而海地的风险是4.3倍(3.5-5.3)。在新生儿后期,多米尼加共和国双胞胎的死亡风险是单胎的1.8倍(1.0-3.1),海地是2.9倍(2.3-3.8)。在多米尼加共和国和海地,双胞胎在1-4岁时的死亡风险与单胎没有显著差异。在这两个国家,低出生体重、缺乏母乳喂养、缺乏或不充分的产前保健、非剖宫产和高出生顺序与双胞胎的高死亡率有关。
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来源期刊
Twin Research and Human Genetics
Twin Research and Human Genetics 医学-妇产科学
CiteScore
1.50
自引率
11.10%
发文量
37
审稿时长
6-12 weeks
期刊介绍: Twin Research and Human Genetics is the official journal of the International Society for Twin Studies. Twin Research and Human Genetics covers all areas of human genetics with an emphasis on twin studies, genetic epidemiology, psychiatric and behavioral genetics, and research on multiple births in the fields of epidemiology, genetics, endocrinology, fetal pathology, obstetrics and pediatrics. Through Twin Research and Human Genetics the society aims to publish the latest research developments in twin studies throughout the world.
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