Evaluation of the efficacy of totally implantable venous access port in breast cancer patients undergoing chemotherapy.

IF 2.9 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Discover. Oncology Pub Date : 2025-03-24 DOI:10.1007/s12672-025-02020-5
Yujuan Guo, Xiaoping Wang, Yaping Huang, Xiong Wu, Yueqiong Wang
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Abstract

Objective: The use of Totally Implantable Venous Access Port (TIVAP) has gained importance in chemotherapy for cancer patients due to its ability to reduce complications compared to conventional central venous catheters. Chemotherapy for breast cancer often requires long-term venous access, and the choice of device can impact both treatment efficacy and patient quality of life. This study randomly divided 355 breast cancer chemotherapy patients, who were treated from January 2022 to January 2023, into the TIVAP group (n = 177) and the control group (n = 178) to evaluate the application effect of TIVAP.

Methods: The patients in the TIVAP group used totally implantable venous access ports, while those in the control group used central venous catheters. We compared the clinical efficacy, ability of daily life, complications, and patient satisfaction between the two groups. Statistical analysis was performed using t-tests for continuous data and χ2 tests for categorical data.

Results: Our results showed that the total clinical efficacy was 96.61% in the TIVAP group and 90.45% in the control group, and the data of the two groups were significantly different (P < 0.05). Before the intervention, the daily living ability scores of the two groups were analyzed, and the difference between the two groups was not significant (P > 0.05). After the intervention, the daily living ability scores of the patients in the TIVAP group (77.41 ± 7.02) were significantly higher than those of the control group (66.75 ± 6.42) (P < 0.05).In terms of complication rate, the TIVAP group was 5.08%, which was significantly lower than that of the control group (12.36%), and the difference between the two groups was significant (P < 0.05).

Conclusion: Therefore, the application of TIVAP in breast cancer chemotherapy patients can effectively reduce the toxic and side effects of chemotherapy, ensure that the patients use the drugs according to the chemotherapy cycle, and then improve the clinical outcome.

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全植入式静脉通路在乳腺癌化疗患者中的疗效评价。
目的:与传统中心静脉导管相比,全植入式静脉通道(TIVAP)能够减少并发症,在癌症患者的化疗中具有重要意义。乳腺癌的化疗通常需要长期的静脉通路,设备的选择会影响治疗效果和患者的生活质量。本研究将2022年1月至2023年1月期间接受乳腺癌化疗的355例患者随机分为TIVAP组(n = 177)和对照组(n = 178),评价TIVAP的应用效果。方法:TIVAP组采用全植入式静脉通道,对照组采用中心静脉导管。比较两组患者的临床疗效、日常生活能力、并发症及患者满意度。对连续资料采用t检验,对分类资料采用χ2检验进行统计分析。结果:我们的结果显示,TIVAP组的总临床疗效为96.61%,对照组为90.45%,两组数据差异有统计学意义(P < 0.05)。干预后,TIVAP组患者日常生活能力评分(77.41±7.02)明显高于对照组(66.75±6.42)。(P)结论:在乳腺癌化疗患者中应用TIVAP可有效降低化疗毒副作用,保证患者按化疗周期用药,进而改善临床预后。
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来源期刊
Discover. Oncology
Discover. Oncology Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
2.40
自引率
9.10%
发文量
122
审稿时长
5 weeks
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