Successful treatment of recalcitrant plantar warts with pulsed dye laser.

IF 1 Q4 DERMATOLOGY Acta Dermatovenerologica Alpina Pannonica et Adriatica Pub Date : 2025-03-01
Rebeka Vukovska, Nebojsha Peshikj, Silvija Duma, Hristina Breshkovska, Ivana Dohcheva Karajovanov, Suzana Nikolovska, Elena Mircevska Arsovska
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Abstract

Introduction: Plantar warts caused by human papillomavirus (HPV) are often resistant to standard treatments, significantly affecting patients' quality of life. Pulsed dye laser (PDL) therapy has emerged as a promising alternative for refractory cases.

Methods: Four patients (three males, one female; ages 15 to 45) with recalcitrant plantar warts unresponsive to cryotherapy, curettage, and topical agents were treated with PDL. Each underwent three sessions spaced 3 weeks apart, using a fluence of 13.50 J/cm² and a pulse duration of 1.5 ms. Outcomes assessed included lesion resolution, recurrence rates, and adverse effects.

Results: All patients achieved complete wart resolution after three PDL sessions. By the second session, vascular coagulation was evident, leading to significant lesion reduction. No adverse effects such as scarring or pigmentation changes were reported, and no recurrences were observed during a 3-month follow-up.

Conclusions: Among laser therapies, PDL demonstrates excellent outcomes with minimal adverse effects in treating refractory plantar warts. Further studies are warranted to validate these findings in larger populations.

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脉冲染料激光成功治疗顽固性足底疣。
导言:由人乳头瘤病毒(HPV)引起的足底疣通常对标准治疗具有耐药性,严重影响患者的生活质量。脉冲染料激光(PDL)治疗已成为难治性病例的一种有希望的替代方法。方法:4例患者(男3例,女1例;顽固性足底疣(年龄15 ~ 45岁)对冷冻疗法、刮除和局部药物无反应,用PDL治疗。每组进行三次实验,间隔3周,使用13.50 J/cm²,脉冲持续时间为1.5 ms。评估的结果包括病变消退、复发率和不良反应。结果:所有患者在三次PDL治疗后均实现了疣的完全消退。到第二阶段,血管凝固明显,导致病变显著减少。在3个月的随访中,未发现瘢痕或色素沉着改变等不良反应,未观察到复发。结论:在激光治疗中,PDL在治疗难治性足底疣方面表现出良好的疗效和最小的不良反应。需要进一步的研究在更大的人群中验证这些发现。
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来源期刊
CiteScore
1.70
自引率
8.30%
发文量
38
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