Predicting preoperative lymph node metastasis in esophageal cancer: Advancement and challenges.

IF 3.2 Q3 ONCOLOGY World journal of clinical oncology Pub Date : 2025-03-24 DOI:10.5306/wjco.v16.i3.102863
Xing-Yan Le, Jun-Bang Feng, Yi Guo, Yue-Qin Zhou, Chuan-Ming Li
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Abstract

Accurate preoperative prediction of lymph node metastasis is crucial for developing clinical management strategies for patients with esophageal cancer. In this letter, we present our insights and opinions on a new nomogram proposed by Xu et al. Although this research has great potential, there are still concerns regarding the small sample size, limited consideration of biological complexity, subjective image segmentation, incomplete image feature extraction and statistical analyses. Furthermore, we discuss how to achieve more robust and accurate predictive performance in future research.

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食管癌术前淋巴结转移预测:进展与挑战。
准确的术前淋巴结转移预测对于制定食管癌患者的临床治疗策略至关重要。虽然这项研究潜力巨大,但仍存在样本量小、对生物复杂性考虑有限、图像分割主观、图像特征提取和统计分析不完整等问题。此外,我们还讨论了如何在未来的研究中实现更稳健、更准确的预测性能。
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期刊介绍: The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.
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