Compounds with potential antitumor activity. VI--2-Alkyl-3-[2-(1,3,4-thiadiazolyl)]-4-thiazolidinones.

Il Farmaco; edizione scientifica Pub Date : 1988-10-01
S Grasso, A Chimirri, P Monforte, G Fenech, M Zappalà, A M Monforte
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Abstract

The antitumor activity of a series of 2-alkyl-3-[2-(1,3,4-thiadiazolyl)]-4-thiazolidinones was tested against the leukemic P 388 tumor system in mice. Only compounds (V-VII) showed significant activity.

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具有潜在抗肿瘤活性的化合物。六世——2-Alkyl-3 - [2 - (1,3, 4-thiadiazolyl)] 4-thiazolidinones。
研究了一系列2-烷基-3-[2-(1,3,4-噻二唑基)]-4-噻唑烷酮类化合物对小鼠白血病p388肿瘤系统的抗肿瘤活性。只有化合物(V-VII)表现出显著的活性。
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