Ni-catalyzed highly regioselective carboborylation bifunctionalization of allenes: access to α-substituted-γ-boro-δ-enoates†

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2024-11-21 DOI:10.1039/d5ob00364d
Jing Wu , Xinman Guo , Jinghan Zou , Ziyu Wang , Weixing Chang , Lingyan Liu , Jing Li
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Abstract

A Ni-catalyzed highly regioselective carboborylation bifunctionalization of allenes was developed, and a series of α-substituted-γ-boro-δ-enoates were generated in good to high yields. This reaction has the advantages of mild reaction conditions, a wide substrate scope and good late-stage modification applications, providing a new strategy for the synthesis of configurationally defined trisubstituted vinyl boron compounds.

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镍催化的高区域选择性烯基碳硼化双功能化:获得α-取代-γ-boro-δ-enoates。
研究了一种镍催化的高区域选择性碳硼化双功能化反应,得到了一系列收率较高的α-取代-γ-boro-δ-enoates。该反应具有反应条件温和、底物范围广、后期修饰应用广等优点,为合成构型明确的三取代乙基硼化合物提供了新的策略。
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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
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