{"title":"Advances in classification and treatment of primary cutaneous lymphomas","authors":"Hong Zheng, Lihua Qiu, Chang Liu, Chen Tian","doi":"10.1007/s00277-025-06311-3","DOIUrl":null,"url":null,"abstract":"<div><p>Primary cutaneous lymphomas (PCLs) are a heterogeneous group of extranodal non-Hodgkin lymphomas, characterized with skin involvement as the primary or predominant manifestation. While early-stage PCLs typically have a favorable prognosis, managing patients with aggressive progression or advaced stages remains a challenge. Recent advancements in molecular biology and sophisticated clinical laboratory tests have significantly improved the classification and management of PCLs, which provide more targeted and effective treatment strategies for patients. This review summarizes the latest classification schemes and therapeutic options for PCLs, with a focus on the latest developments and future directions in the field.</p></div>","PeriodicalId":8068,"journal":{"name":"Annals of Hematology","volume":"104 4","pages":"2143 - 2157"},"PeriodicalIF":2.4000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00277-025-06311-3.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Hematology","FirstCategoryId":"3","ListUrlMain":"https://link.springer.com/article/10.1007/s00277-025-06311-3","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Primary cutaneous lymphomas (PCLs) are a heterogeneous group of extranodal non-Hodgkin lymphomas, characterized with skin involvement as the primary or predominant manifestation. While early-stage PCLs typically have a favorable prognosis, managing patients with aggressive progression or advaced stages remains a challenge. Recent advancements in molecular biology and sophisticated clinical laboratory tests have significantly improved the classification and management of PCLs, which provide more targeted and effective treatment strategies for patients. This review summarizes the latest classification schemes and therapeutic options for PCLs, with a focus on the latest developments and future directions in the field.
期刊介绍：
Annals of Hematology covers the whole spectrum of clinical and experimental hematology, hemostaseology, blood transfusion, and related aspects of medical oncology, including diagnosis and treatment of leukemias, lymphatic neoplasias and solid tumors, and transplantation of hematopoietic stem cells. Coverage includes general aspects of oncology, molecular biology and immunology as pertinent to problems of human blood disease. The journal is associated with the German Society for Hematology and Medical Oncology, and the Austrian Society for Hematology and Oncology.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
