Zi Wang, Nadim K Saadé, Robert J Panetta, Parisa A Ariya
{"title":"A HoLDI mass spectrometry platform for airborne nanoplastic detection.","authors":"Zi Wang, Nadim K Saadé, Robert J Panetta, Parisa A Ariya","doi":"10.1038/s42004-025-01483-5","DOIUrl":null,"url":null,"abstract":"<p><p>There are no established protocols for nanoplastic detection within complex environmental matrices. Mass spectrometry (MS) analysis of environmental nanoplastics is impeded by methodological constraints. We present a versatile platform evolved from matrix-assisted laser desorption/ionization (MALDI) MS for airborne nano/microplastic research. The 3D-printed hollow-laser desorption/ionization (HoLDI) target enables efficient, high-throughput analysis of aerosols collected on simple substrates without pre/post-treatments. HoLDI-MS determines the chemical composition and relative quantity of real-world airborne nano/microplastics, while used with conventional portable samplers and particle analyzers. Polyethylene, polyethylene glycol, and polydimethylsiloxanes are detected in an indoor environment, with a higher amount in the micro-sized range. Polycyclic aromatic hydrocarbons present in an outdoor setting, with a higher quantity in the nano-sized range. Morphological and elemental data provide additional evidence for observed contaminants and support multidisciplinary research interests. HoLDI holds promise as a standardized analytical framework for any air or water samples, facilitating research harmonization worldwide.</p>","PeriodicalId":10529,"journal":{"name":"Communications Chemistry","volume":"8 1","pages":"90"},"PeriodicalIF":6.2000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937337/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Communications Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1038/s42004-025-01483-5","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
There are no established protocols for nanoplastic detection within complex environmental matrices. Mass spectrometry (MS) analysis of environmental nanoplastics is impeded by methodological constraints. We present a versatile platform evolved from matrix-assisted laser desorption/ionization (MALDI) MS for airborne nano/microplastic research. The 3D-printed hollow-laser desorption/ionization (HoLDI) target enables efficient, high-throughput analysis of aerosols collected on simple substrates without pre/post-treatments. HoLDI-MS determines the chemical composition and relative quantity of real-world airborne nano/microplastics, while used with conventional portable samplers and particle analyzers. Polyethylene, polyethylene glycol, and polydimethylsiloxanes are detected in an indoor environment, with a higher amount in the micro-sized range. Polycyclic aromatic hydrocarbons present in an outdoor setting, with a higher quantity in the nano-sized range. Morphological and elemental data provide additional evidence for observed contaminants and support multidisciplinary research interests. HoLDI holds promise as a standardized analytical framework for any air or water samples, facilitating research harmonization worldwide.
期刊介绍：
Communications Chemistry is an open access journal from Nature Research publishing high-quality research, reviews and commentary in all areas of the chemical sciences. Research papers published by the journal represent significant advances bringing new chemical insight to a specialized area of research. We also aim to provide a community forum for issues of importance to all chemists, regardless of sub-discipline.
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