Ethanol Infusion Therapy for Incessant Atrial Tachycardia Arising From the Distal Left Atrial Appendage

IF 2.6 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular Electrophysiology Pub Date : 2025-03-25 DOI:10.1111/jce.16662
Jia-Yin Li, Bin-Feng Mo
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Abstract

Introduction

Atrial tachycardias (AT) originating from the distal left atrial appendage (LAAd) are rare and pose significant challenges during catheter ablation. This report describes a case of incessant AT arising from the LAAd that was successfully treated using ethanol infusion therapy.

Methods

A 70-year-old male patient with a history of incessant AT was referred to our center. Electrophysiological study and activation mapping were performed, revealing a focal AT originating from the LAAd with a cycle length of 544 ms (110 bpm).

Results

Endocardial catheter ablation attempts within the left atrial appendage (LAA) failed to terminate the tachycardia. The LAA vein was difficult to visualize but was detected using a guidewire. Ethanol infusion into the LAA vein resulted in immediate termination of the LAAd AT. The patient remained in sinus rhythm during a 14-month follow-up period.

Conclusions

Chemical ablation with ethanol infusion may serve as an effective alternative therapeutic strategy for managing focal ATs originating from the LAAd, although the success of this approach is contingent upon the anatomical accessibility and distribution of the LAA vein.

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乙醇输注治疗左心耳远端不间断房性心动过速。
导读:起源于左心耳远端(LAAd)的房性心动过速(AT)是罕见的,对导管消融构成了重大挑战。本报告描述了一例由LAAd引起的持续AT,使用乙醇输注疗法成功治疗。方法:一位70岁男性患者,既往有不间断AT病史。电生理研究和激活图谱显示了一个起源于LAAd的病灶AT,周期长度为544 ms (110 bpm)。结果:心内膜导管在左心耳(LAA)内消融未能终止心动过速。LAA静脉很难看到,但使用导丝检测。乙醇输注到LAA静脉导致LAAd AT立即终止。在14个月的随访期间,患者仍保持窦性心律。结论:化学消融与乙醇输注可能是治疗起源于LAAd的局灶性ATs的有效替代治疗策略,尽管该方法的成功取决于LAA静脉的解剖可达性和分布。
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来源期刊
CiteScore
5.20
自引率
14.80%
发文量
433
审稿时长
3-6 weeks
期刊介绍: Journal of Cardiovascular Electrophysiology (JCE) keeps its readership well informed of the latest developments in the study and management of arrhythmic disorders. Edited by Bradley P. Knight, M.D., and a distinguished international editorial board, JCE is the leading journal devoted to the study of the electrophysiology of the heart.
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