Microangiopathic Hemolytic Anemia as paraneoplastic syndrome secondary to Pheochromocytoma: a rare case report.

IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL Oxford Medical Case Reports Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI:10.1093/omcr/omaf034
Omar Q Heih, Mahmoud R Manasra, Ziad F Salah, Monther M Hroub, Hassan Arafat, Bashir I Abu Aqeel, Ahmad G Hammouri
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Abstract

Pheochromocytoma is a rare adrenal tumor that secretes catecholamines. Microangiopathic hemolytic anemia, a kind of hemolytic anemia in which erythrocytes are destroyed in microscopic blood capillaries, resulting in fragmentation and hemolysis. This condition is an uncommon but significant consequence observed most commonly in malignant pheochromocytoma. In this case report, we present a 21-year-old single female with a strong family history of endocrine malignancy. She was referred to our hospital for chemotherapy due to a diagnosis of malignant pheochromocytoma, which had metastasized to the urinary bladder, bone, and lung. Additionally, she developed microangiopathic hemolytic anemia as a paraneoplastic syndrome.

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嗜铬细胞瘤继发于微血管病性溶血性贫血:罕见病例报告。
嗜铬细胞瘤是一种罕见的肾上腺肿瘤,分泌儿茶酚胺。微血管病溶血性贫血,是红细胞在微血管中被破坏,导致碎裂、溶血的一种溶血性贫血。这种情况不常见,但在恶性嗜铬细胞瘤中最常见。在这个病例报告中,我们提出了一个21岁的单身女性,有强烈的内分泌恶性家族史。由于诊断为恶性嗜铬细胞瘤,已转移到膀胱、骨骼和肺部,她被转介到我们医院接受化疗。此外,她发展为微血管病溶血性贫血作为副肿瘤综合征。
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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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