Biostimulatory Fillers to Treat Post-liposuction Skin Irregularities.

Q2 Medicine Journal of Clinical and Aesthetic Dermatology Pub Date : 2025-03-01

Stefania Guida, Ilaria Proietti, Claudio Conforti, Carmen Cantisani, Nicola Zerbinati, Giovanni Pellacani, Hassan Galadari

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Abstract

Background: Treatment of post-liposuction skin irregularities (PLSI), a complication of liposuction, can be challenging.

Objective: Considering the increasing request of treatment of PLSI, the aim of this study is to evaluate the efficacy and safety of CaHA diluted/hyperdiluted to PLSI.

Methods: A retrospective study on a total of eight PLSI areas in six women treated with CaHA diluted/hyperdiluted was performed. Efficacy was estimated on pictures of affected areas collected before and four months after treatment, according to the recently validated PLSI scale and Student's t-test for paired samples was performed to analyze data. Eventual adverse events were used to evaluate safety.

Results: Our results showed a statistically significant improvement of number and depth of depressions and a trend toward reduction of skin laxity.

Conclusion: This study reported the efficacy and safety of CaHA diluted/hyperdiluted for PLSI treatment. Larger studies are encouraged to support the results of this pilot study.

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生物刺激填充物治疗吸脂后皮肤不规则。

背景：吸脂后皮肤不规则（PLSI）是吸脂术的并发症之一，其治疗具有挑战性。目的：考虑到PLSI治疗需求的增加，本研究旨在评价CaHA稀释/超稀释治疗PLSI的疗效和安全性。方法：对6例经CaHA稀释/超稀释治疗的8个PLSI区域进行回顾性研究。根据最近验证的PLSI量表，根据治疗前和治疗后四个月收集的患处图片估计疗效，并对配对样本进行学生t检验来分析数据。最终不良事件用于评估安全性。结果：我们的结果显示统计上显著改善了凹陷的数量和深度，并有减少皮肤松弛的趋势。结论：本研究报道了CaHA稀释/超稀释治疗PLSI的有效性和安全性。鼓励更大规模的研究来支持这一初步研究的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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