Hend Algadi, Mohammed Abdelfatah Alhoot, Laith A Yaaqoob
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引用次数: 0
Abstract
A substantial threat to worldwide health, the proliferation of antibiotic-resistant bacteria compels researchers to seek innovative antibacterial substances. This systematic review assesses the role of nanoparticles, particularly Calcium oxide and Silicon oxide nanoparticles, in infection control. The article examines the mechanisms by which these nanoparticles act against various bacteria and evaluates their potential as novel agents in infection control strategies. A systematic literature search from 2015 to 2024 encompassing Web of Science, PubMed, Wiley, Science Direct, and Google Scholar, yielded 70 publications meeting the review criteria. This comprehensive methodology provides a thorough understanding of the capabilities and limitations of Calcium oxide and Silicon oxide nanoparticles as antibacterial agents. The review aims to build a solid foundation for the utilization of nanoparticles in addressing the obstacles presented by antibiotic resistance by combining data from various investigations. Additionally, it aims to explore the safety and environmental implications associated with their use in clinical and environmental settings, providing a comprehensive analysis that may contribute to future studies and real-world applications in the field of antimicrobial technology.
抗生素耐药细菌的激增是对全球健康的重大威胁，迫使研究人员寻求创新的抗菌物质。本系统综述评估了纳米颗粒，特别是氧化钙和氧化硅纳米颗粒在感染控制中的作用。本文研究了这些纳米颗粒对抗各种细菌的机制，并评估了它们作为感染控制策略中的新型药物的潜力。从2015年到2024年，包括Web of Science、PubMed、Wiley、Science Direct和b谷歌Scholar在内的系统文献检索产生了70篇符合评审标准的出版物。这种综合的方法提供了氧化钙和氧化硅纳米颗粒作为抗菌剂的能力和局限性的透彻理解。本文旨在结合各种研究数据，为纳米颗粒在解决抗生素耐药性障碍中的应用奠定坚实的基础。此外，它旨在探索与临床和环境设置中使用相关的安全性和环境影响，提供一个全面的分析，可能有助于抗菌技术领域的未来研究和实际应用。
期刊介绍：
Journal of Applied Biomedicine promotes translation of basic biomedical research into clinical investigation, conversion of clinical evidence into practice in all medical fields, and publication of new ideas for conquering human health problems across disciplines.
Providing a unique perspective, this international journal publishes peer-reviewed original papers and reviews offering a sensible transfer of basic research to applied clinical medicine. Journal of Applied Biomedicine covers the latest developments in various fields of biomedicine with special attention to cardiology and cardiovascular diseases, genetics, immunology, environmental health, toxicology, neurology and oncology as well as multidisciplinary studies. The views of experts on current advances in nanotechnology and molecular/cell biology will be also considered for publication as long as they have a direct clinical impact on human health. The journal does not accept basic science research or research without significant clinical implications. Manuscripts with innovative ideas and approaches that bridge different fields and show clear perspectives for clinical applications are considered with top priority.
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