Optimizing brain tumor detection in MRI scans through InceptionResNetV2 and deep stacked Autoencoders with SwiGLU activation and sparsity regularization.

IF 1.9 Q2 MULTIDISCIPLINARY SCIENCES MethodsX Pub Date : 2025-03-07 eCollection Date: 2025-06-01 DOI:10.1016/j.mex.2025.103255
Vishal Awasthi, Mamta Tiwari, Amit Yadav, Gesu Thakur, Mamata Mayee Panda, Hemant Kumar, Shivneet Tripathi
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Abstract

This study presents an automated framework for brain tumor classification aimed at accurately distinguishing tumor types in MRI images. The proposed model integrates InceptionResNetV2 for feature extraction with Deep Stacked Autoencoders (DSAEs) for classification, enhanced by sparsity regularization and the SwiGLU activation function. InceptionResNetV2, pre-trained on ImageNet, was fine-tuned to extract multi-scale features, while the DSAE structure compressed these features to highlight critical attributes essential for classification. The approach achieved high performance, reaching an overall accuracy of 99.53 %, precision of 98.27 %, recall of 99.21 %, specificity of 98.73 %, and an F1-score of 98.74 %. These results demonstrate the model's efficacy in accurately categorizing glioma, meningioma, pituitary tumors, and non-tumor cases, with minimal misclassifications. Despite its success, limitations include the model's dependency on pre-trained weights and significant computational resources. Future studies should address these limitations by enhancing interpretability, exploring domain-specific transfer learning, and validating on diverse datasets to strengthen the model's utility in real-world settings. Overall, the InceptionResNetV2 integrated with DSAEs, sparsity regularization, and SwiGLU offers a promising solution for reliable and efficient brain tumor diagnosis in clinical environments.•Leveraging a pre-trained InceptionResNetV2 model to capture multi-scale features from MRI data.•Utilizing Deep Stacked Autoencoders with sparsity regularization to emphasize critical attributes for precise classification.•Incorporating the SwiGLU activation function to capture complex, non-linear patterns within the data.

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通过inseptionresnetv2和SwiGLU激活和稀疏正则化的深度堆叠自编码器优化MRI扫描中的脑肿瘤检测。
本研究提出了一种自动化的脑肿瘤分类框架,旨在准确区分MRI图像中的肿瘤类型。该模型集成了用于特征提取的InceptionResNetV2和用于分类的深度堆叠自编码器(Deep Stacked Autoencoders, DSAEs),并通过稀疏正则化和SwiGLU激活函数进行增强。在ImageNet上进行预训练的InceptionResNetV2被微调以提取多尺度特征,而DSAE结构压缩这些特征以突出分类所需的关键属性。该方法取得了良好的性能,总体准确率为99.53%,精密度为98.27%,召回率为99.21%,特异性为98.73%,f1评分为98.74%。这些结果证明了该模型在准确分类胶质瘤、脑膜瘤、垂体瘤和非肿瘤病例方面的有效性,并且错误分类最小。尽管取得了成功,但该模型的局限性包括依赖于预训练的权重和大量的计算资源。未来的研究应该通过增强可解释性,探索特定领域的迁移学习,以及在不同的数据集上验证来加强模型在现实世界中的实用性来解决这些局限性。总体而言,InceptionResNetV2集成了DSAEs、稀疏正则化和SwiGLU,为临床环境中可靠、高效的脑肿瘤诊断提供了一个有前景的解决方案。•利用预训练的InceptionResNetV2模型从MRI数据中捕获多尺度特征。•利用深度堆叠自动编码器与稀疏性正则化,以强调精确分类的关键属性。•结合SwiGLU激活功能,捕捉数据中复杂的非线性模式。
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来源期刊
MethodsX
MethodsX Health Professions-Medical Laboratory Technology
CiteScore
3.60
自引率
5.30%
发文量
314
审稿时长
7 weeks
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