Yuhan Wang, Ling Jiang, Jie Wang, Yuanshuai Huang, Ya Dong
{"title":"Utilization of TEP miRNAs in tumor proliferation, diagnostic evaluation, therapeutic intervention, and prognostic assessment.","authors":"Yuhan Wang, Ling Jiang, Jie Wang, Yuanshuai Huang, Ya Dong","doi":"10.1007/s11033-025-10433-2","DOIUrl":null,"url":null,"abstract":"<p><p>According to the most recent 2022 statistics, China accounts for 4.82 million cancer patients, leading globally in prevalence. Early detection and intervention remain the most effective strategies for tumor prevention, treatment, and mortality reduction. There is an urgent need to enhance capabilities in cancer diagnosis and prevention. This study examines the association between tumor-educated platelet (TEP) microRNAs (miRNAs) and malignancies, as well as the role of TEP miRNAs in common cancers. TEP miRNAs offer significant advantages over tissue biopsies, conventional tumor biomarkers, and circulating miRNAs, including simplified sampling procedures, efficient monitoring, and longitudinal assessment of therapeutic dynamics. These advantages are instrumental in advancing tumor screening, diagnosis, treatment, and monitoring.</p>","PeriodicalId":18755,"journal":{"name":"Molecular Biology Reports","volume":"52 1","pages":"343"},"PeriodicalIF":2.8000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular Biology Reports","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s11033-025-10433-2","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
According to the most recent 2022 statistics, China accounts for 4.82 million cancer patients, leading globally in prevalence. Early detection and intervention remain the most effective strategies for tumor prevention, treatment, and mortality reduction. There is an urgent need to enhance capabilities in cancer diagnosis and prevention. This study examines the association between tumor-educated platelet (TEP) microRNAs (miRNAs) and malignancies, as well as the role of TEP miRNAs in common cancers. TEP miRNAs offer significant advantages over tissue biopsies, conventional tumor biomarkers, and circulating miRNAs, including simplified sampling procedures, efficient monitoring, and longitudinal assessment of therapeutic dynamics. These advantages are instrumental in advancing tumor screening, diagnosis, treatment, and monitoring.
期刊介绍：
Molecular Biology Reports publishes original research papers and review articles that demonstrate novel molecular and cellular findings in both eukaryotes (animals, plants, algae, funghi) and prokaryotes (bacteria and archaea).The journal publishes results of both fundamental and translational research as well as new techniques that advance experimental progress in the field and presents original research papers, short communications and (mini-) reviews.
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