Occlusive primary endobronchial amyloid tumour: a rare case

IF 7.7 1区 医学 Q1 RESPIRATORY SYSTEM Thorax Pub Date : 2025-03-27 DOI:10.1136/thorax-2023-221189
Joseph Michael Curran, Daniel Steinfort, Belinda Liu
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Abstract

A female aged 69 year never smoker presented with 4 months of non-resolving productive cough and shortness of breath on exertion following mild COVID-19 infection. Her background history was significant for tuberculosis infection in 1996, for which she completed a full course of treatment. An initial CT scan of the chest found bulky left hilar and mediastinal lymphadenopathy with heterogeneous calcification. A subsequent fluorodeoxyglucose-positron emission tomography CT demonstrated intense metabolic activity in these lymph nodes. Further CT chest with contrast (figure 1a, c) showed interval development of new left upper lobe collapse with stable lymphadenopathy. Lung function was within normal limits. Bronchoscopic examination demonstrated a large obstructing mass in the left upper lobe bronchus (figure 2a), with subtotal occlusion of the left lower lobe bronchus (figure …
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原发性闭塞性支气管内淀粉样瘤1例
一名69岁女性,从不吸烟,在轻度COVID-19感染后出现4个月无缓解的生产性咳嗽和用力时呼吸短促。她在1996年的结核病感染背景史具有重要意义,为此她完成了整个疗程的治疗。胸部初始CT扫描发现左侧肺门和纵隔肿大伴异质性钙化。随后的氟脱氧葡萄糖正电子发射断层扫描CT显示这些淋巴结有强烈的代谢活动。进一步胸部CT对比(图1a, c)显示间断性左上肺叶塌陷伴稳定淋巴结病变。肺功能正常。支气管镜检查显示左支气管上叶有一大块阻塞物(图2a),左下叶支气管次全闭塞(图…)
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来源期刊
Thorax
Thorax 医学-呼吸系统
CiteScore
16.10
自引率
2.00%
发文量
197
审稿时长
1 months
期刊介绍: Thorax stands as one of the premier respiratory medicine journals globally, featuring clinical and experimental research articles spanning respiratory medicine, pediatrics, immunology, pharmacology, pathology, and surgery. The journal's mission is to publish noteworthy advancements in scientific understanding that are poised to influence clinical practice significantly. This encompasses articles delving into basic and translational mechanisms applicable to clinical material, covering areas such as cell and molecular biology, genetics, epidemiology, and immunology.
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