Inside Front Cover: Chemical Process Development in the Pharmaceutical Industry in Europe: Insights and Perspectives from Industry Scientists (Angew. Chem. Int. Ed. 19/2025)
Joachim Krueger, André P. Dieskau, Jorma Hassfeld, Joerg Gries, Oliver Block, Hilmar Weinmann, Daniel Kaufmann, Stefan Hildbrand, Volker Kraft, Robert Moeckel, Juan R. Dehli, Ulrich Scholz, Carl Friedrich Nising
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Abstract
Chemical Process Development of Active Pharmaceutical Ingredients (API) is a critical task in the pharmaceutical industry. The cover artwork illustrates the scale-up pathway from lab scale via microreactors to pilot scale reactors. In a clockwise arrangement, it highlights key drivers for process development (speed, sustainability, cost, global networks, digitalization and people) as well as selected API modalities (radiotherapeutics, small molecules, oligonucleotides and antibody drug conjugates). Read more in the Scientific Perspective by Ulrich Scholz, Carl Friedrich Nising et al. (e202420719).
活性药物成分（API）的化学工艺开发是制药行业的一项重要任务。封面插图说明了从实验室规模通过微反应器到中试规模反应器的放大途径。以顺时针方向排列，它突出了工艺开发的关键驱动因素（速度、可持续性、成本、全球网络、数字化和人员）以及选定的API模式（放射治疗、小分子、寡核苷酸和抗体药物偶联物）。请参阅Ulrich Scholz， Carl Friedrich Nising等人的《科学视角》（e202420719）。
期刊介绍：
Angewandte Chemie, a journal of the German Chemical Society (GDCh), maintains a leading position among scholarly journals in general chemistry with an impressive Impact Factor of 16.6 (2022 Journal Citation Reports, Clarivate, 2023). Published weekly in a reader-friendly format, it features new articles almost every day. Established in 1887, Angewandte Chemie is a prominent chemistry journal, offering a dynamic blend of Review-type articles, Highlights, Communications, and Research Articles on a weekly basis, making it unique in the field.
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