Comparative Assessment of Manual Segmentation of Cerebral Infarction Lesions in Experimental Animals Based on Magnetic Resonance Imaging Using Artificial Intelligence.

IF 0.6 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL Bulletin of Experimental Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2025-03-28 DOI:10.1007/s10517-025-06366-2
I L Gubskiy, D D Namestnikova, E A Cherkashova, I S Gumin, V V Kurilo, V P Chekhonin, K N Yarygin
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Abstract

The aim of this study was to evaluate the quality of manual segmentation of cerebral infarction lesions in experimental animals with modeled brain infarct based on magnetic resonance imaging compared to an automated artificial intelligence approach. For automated infarct segmentation, an artificial intelligence system with the Swin-UNETR architecture was used, while manual segmentation was performed by four independent researchers. It was shown that manual segmentation exhibits significant variability, especially when small brain infarct lesions are analyzed. The obtained data emphasize the need for standardizing methods and applying automated systems to improve the accuracy and reproducibility of the results.

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利用人工智能对基于磁共振成像的实验动物脑梗塞病灶手动分割进行比较评估
本研究的目的是评估基于磁共振成像的脑梗死模型实验动物脑梗死病变人工分割的质量,并将其与自动化人工智能方法进行比较。对于自动梗死分割,使用具有swan - unetr架构的人工智能系统,而手动分割由四位独立研究人员进行。研究表明,人工分割表现出显著的可变性,特别是当分析小脑梗死灶时。获得的数据强调需要标准化的方法和应用自动化系统,以提高结果的准确性和可重复性。
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来源期刊
Bulletin of Experimental Biology and Medicine
Bulletin of Experimental Biology and Medicine 医学-医学:研究与实验
CiteScore
1.50
自引率
14.30%
发文量
265
审稿时长
2 months
期刊介绍: Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.
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