Screening in Gastrointestinal Malignancies-Recent Trials and Advancements.

IF 4.4 2区 医学 Q1 ONCOLOGY Cancers Pub Date : 2025-03-13 DOI:10.3390/cancers17060975
Natalia Czerw, Andrzej Deptała, Anna Badowska-Kozakiewicz, Aleksandra Czerw, Olga Partyka, Monika Pajewska, Katarzyna Sygit, Magdalena Michalska, Izabela Gąska, Grażyna Dykowska, Zofia Sienkiewicz, Elżbieta Grochans, Szymon Grochans, Anna Cybulska, Daria Schneider-Matyka, Ewa Bandurska, Weronika Ciećko, Jaroslaw Drobnik, Piotr Pobrotyn, Joanna Furtak-Pobrotyn, Dagmara Pokorna-Kałwak, Urszula Grata-Borkowska, Michal Marczak, Petre Iltchev, Remigiusz Kozlowski
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Abstract

Gastrointestinal cancers, especially colorectal cancer, represent a major health care issue. According to the data, the incidence of these cancers exceeds 50/100,000, mainly in high-income countries. Risk factors for the disease include genetic factors (i.e., Lynch syndrome) and lifestyle factors, e.g., overweight and obesity, smoking tobacco products, low-fiber diet, and low physical activity. When diagnosed early, gastrointestinal cancers can, in most cases, be effectively treated. This review focuses on the presentation of research in the area of screening and its results. It provides insights into current trends in research on methods of early cancer detection and improving screening reporting. Differing levels of screening reporting are one of the main challenges faced by researchers in this field. Research on this issue should be conducted in parallel with research on methods of early diagnosis. Finally, the development of diagnostic methods and communication with patients are important elements of public health.

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胃肠道恶性肿瘤的筛查-最近的试验和进展。
胃肠道癌症,尤其是结肠直肠癌,是一个重大的医疗保健问题。数据显示,这些癌症的发病率超过 50/100,000,主要发生在高收入国家。该疾病的风险因素包括遗传因素(如林奇综合征)和生活方式因素,如超重和肥胖、吸烟、低纤维饮食和运动量少。如能及早诊断,大多数胃肠道癌症都能得到有效治疗。本综述重点介绍筛查领域的研究及其结果。它深入探讨了早期癌症检测方法和改进筛查报告的当前研究趋势。筛查报告水平参差不齐是该领域研究人员面临的主要挑战之一。对这一问题的研究应与早期诊断方法的研究同步进行。最后,诊断方法的开发和与患者的沟通是公共卫生的重要内容。
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来源期刊
Cancers
Cancers Medicine-Oncology
CiteScore
8.00
自引率
9.60%
发文量
5371
审稿时长
18.07 days
期刊介绍: Cancers (ISSN 2072-6694) is an international, peer-reviewed open access journal on oncology. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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