Risk Factors for Suicide Among Head and Neck Cancer Patients: A Systematic Review and Meta-Analysis

IF 2.2 3区医学 Q1 OTORHINOLARYNGOLOGY Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-03-27 DOI:10.1002/hed.28145

Sami I. Nassar, Ryan A. Durgham, Shaun A. Nguyen, Jason G. Newman, Alexandra E. Kejner, William G. Albergotti

{"title":"Risk Factors for Suicide Among Head and Neck Cancer Patients: A Systematic Review and Meta-Analysis","authors":"Sami I. Nassar, Ryan A. Durgham, Shaun A. Nguyen, Jason G. Newman, Alexandra E. Kejner, William G. Albergotti","doi":"10.1002/hed.28145","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Head and neck cancer (HNC) patients have an elevated suicide risk. This study examines suicide risk factors among HNC patients.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Databases were reviewed through June 2024 for articles examining HNC patient suicide. HNC patients, non-HNC cancer patients, and suicide case numbers were stratified by patient variables. Meta-analyses of proportions and relative risk (RR) were performed.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Twenty-one studies with 1 610 031 HNC and 16 857 218 non-HNC cancer patients were included. HNC patients had a higher suicide risk than non-HNC cancer (RR 2.369) and general population (RR 26.991) cohorts. Non-Hispanic ethnicity (RR 3.773), male sex (RR 2.721), and oropharyngeal (RR 1.241) or laryngeal (RR 1.182) cancers increased risk. Being Black (RR 0.316), Hispanic (RR 0.265), and female (RR 0.367) decreased risk. Excluding studies only examining laryngeal cancer intensified sex and race effects on suicide risk.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>HNC patients have a higher suicide risk than other cancer patients. Laryngeal cancer attenuates the effects of other variables.</p>\n </section>\n </div>","PeriodicalId":55072,"journal":{"name":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","volume":"47 8","pages":"2231-2247"},"PeriodicalIF":2.2000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Head and Neck-Journal for the Sciences and Specialties of the Head and Neck","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/hed.28145","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Head and neck cancer (HNC) patients have an elevated suicide risk. This study examines suicide risk factors among HNC patients.

Methods

Databases were reviewed through June 2024 for articles examining HNC patient suicide. HNC patients, non-HNC cancer patients, and suicide case numbers were stratified by patient variables. Meta-analyses of proportions and relative risk (RR) were performed.

Results

Twenty-one studies with 1 610 031 HNC and 16 857 218 non-HNC cancer patients were included. HNC patients had a higher suicide risk than non-HNC cancer (RR 2.369) and general population (RR 26.991) cohorts. Non-Hispanic ethnicity (RR 3.773), male sex (RR 2.721), and oropharyngeal (RR 1.241) or laryngeal (RR 1.182) cancers increased risk. Being Black (RR 0.316), Hispanic (RR 0.265), and female (RR 0.367) decreased risk. Excluding studies only examining laryngeal cancer intensified sex and race effects on suicide risk.

Conclusions

HNC patients have a higher suicide risk than other cancer patients. Laryngeal cancer attenuates the effects of other variables.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

头颈癌患者自杀的风险因素：系统回顾与元分析》。

背景：头颈癌（HNC）患者有较高的自杀风险。本研究探讨HNC患者的自杀风险因素。方法：回顾数据库中截至2024年6月的有关HNC患者自杀的文章。HNC患者、非HNC癌症患者和自杀病例数按患者变量分层。对比例和相对危险度（RR）进行meta分析。结果：纳入21项研究，HNC患者1 610 031例，非HNC患者16 857 218例。HNC患者的自杀风险高于非HNC患者（RR为2.369）和普通人群（RR为26.991）。非西班牙裔（RR 3.773）、男性（RR 2.721）和口咽癌（RR 1.241）或喉癌（RR 1.182）增加了风险。黑人（RR 0.316）、西班牙裔（RR 0.265）和女性（RR 0.367）降低了风险。排除仅检查喉癌的研究，性别和种族对自杀风险的影响增强。结论：HNC患者的自杀风险高于其他癌症患者。喉癌减弱了其他变量的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.