Nightmare case of repeated hemorrhagic pancreatitis due to pancreatic head cancer in the acute stage after two-stage lung transplantation

JHLT Open Pub Date : 2025-05-01 Epub Date: 2025-03-11 DOI:10.1016/j.jhlto.2025.100245
Tatsuya Hayashi , Shin Tanaka , Tsuyoshi Ryuko , Yasuaki Tomioka , Kentaroh Miyoshi , Mikio Okazaki , Seiichiro Sugimoto , Shinichi Toyooka
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Abstract

In Japan, due to the shortage of deceased organ donors, the use of two-stage lung transplantation (LTx), specifically sequential single-lung transplants (SSLTs), has been increasing. This approach starts immunosuppressive therapy after the first transplantation, which increases the risk of malignancies. Here, we present a case of fatal perioperative hemorrhagic pancreatitis caused by pancreatic head cancer following SSLTs. This case highlights significant challenges in diagnosis and treatment.
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两段式肺移植术后急性期胰头癌导致反复出血性胰腺炎的噩梦病例
在日本,由于已故器官捐献者短缺,两阶段肺移植(LTx),特别是连续单肺移植(SSLTs)的使用越来越多。这种方法在第一次移植后开始免疫抑制治疗,这增加了恶性肿瘤的风险。在此,我们介绍了一例因胰头癌导致的致命性围手术期出血性胰腺炎病例。该病例凸显了诊断和治疗中的重大挑战。
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