{"title":"Nightmare case of repeated hemorrhagic pancreatitis due to pancreatic head cancer in the acute stage after two-stage lung transplantation","authors":"Tatsuya Hayashi , Shin Tanaka , Tsuyoshi Ryuko , Yasuaki Tomioka , Kentaroh Miyoshi , Mikio Okazaki , Seiichiro Sugimoto , Shinichi Toyooka","doi":"10.1016/j.jhlto.2025.100245","DOIUrl":null,"url":null,"abstract":"<div><div>In Japan, due to the shortage of deceased organ donors, the use of two-stage lung transplantation (LTx), specifically sequential single-lung transplants (SSLTs), has been increasing. This approach starts immunosuppressive therapy after the first transplantation, which increases the risk of malignancies. Here, we present a case of fatal perioperative hemorrhagic pancreatitis caused by pancreatic head cancer following SSLTs. This case highlights significant challenges in diagnosis and treatment.</div></div>","PeriodicalId":100741,"journal":{"name":"JHLT Open","volume":"8 ","pages":"Article 100245"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JHLT Open","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950133425000400","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/11 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In Japan, due to the shortage of deceased organ donors, the use of two-stage lung transplantation (LTx), specifically sequential single-lung transplants (SSLTs), has been increasing. This approach starts immunosuppressive therapy after the first transplantation, which increases the risk of malignancies. Here, we present a case of fatal perioperative hemorrhagic pancreatitis caused by pancreatic head cancer following SSLTs. This case highlights significant challenges in diagnosis and treatment.