Cover Feature: Unlocking Lignin′s Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules (ChemSusChem 7/2025)

IF 6.6 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY ChemSusChem Pub Date : 2025-04-01 DOI:10.1002/cssc.202580702

Vânia Brissos, Márcia Rénio, Magdalena A. Lejmel, Ricardo Estevinho, M. Paula Robalo, M. Rita Ventura, Lígia O. Martins

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Abstract

The Cover Feature shows laccases as biocatalysts with high potential in lignocellulose biorefineries. Protein engineering has enhanced their efficiency for valorizing lignin monomers into value-added biologically active molecules. This biocatalytic process is solvent-free, achieves faster reaction times, uses lower amounts of enzyme, and delivers excellent yields (up to 100 %). The work advances lignin combinatory chemistry knowledge and marks a step forward in producing sustainable and eco-friendly natural dimeric compounds for medicinal chemistry and polymer synthesis. More information can be found in the Research Article by M. P. Robalo, M. R. Ventura, L. O. Martins and co-workers (DOI: 10.1002/cssc.202401386). Cover design: Joel Arruda (ITQB-NOVA Science Communication Office).

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封面专题：释放木质素的潜力：工程细菌漆酶生产生物活性分子（ChemSusChem 7/2025）

封面特征显示漆酶作为生物催化剂在木质纤维素生物炼制中具有很高的潜力。蛋白质工程提高了木质素单体转化为增值生物活性分子的效率。这种生物催化过程无溶剂，实现更快的反应时间，使用更少的酶，并提供优异的收率（高达100%）。这项工作促进了木质素组合化学知识的发展，标志着在生产可持续和环保的天然二聚体化合物用于药物化学和聚合物合成方面迈出了一步。更多信息可以在m.p.的研究文章中找到。罗巴洛，m.r。文图拉，洛杉矶。Martins和同事（DOI: 10.1002/cssc.202401386）。封面设计：Joel Arruda （ITQB-NOVA科学传播办公室）。

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来源期刊

ChemSusChem 化学-化学综合

CiteScore

15.80

自引率

4.80%

发文量

555

审稿时长

1.8 months

期刊介绍： ChemSusChem Impact Factor (2016): 7.226 Scope: Interdisciplinary journal Focuses on research at the interface of chemistry and sustainability Features the best research on sustainability and energy Areas Covered: Chemistry Materials Science Chemical Engineering Biotechnology