{"title":"Expedient conversion of tertiary α-diazoamide to 5-amino-1,2,3-thiadiazole through a thionation-cyclization cascade","authors":"Xiao-Jing Tian, Guodong Hu, Mei-Hua Shen, Hua-Dong Xu","doi":"10.1016/j.tetlet.2025.155564","DOIUrl":null,"url":null,"abstract":"<div><div>Thionation of tertiary α-diazoamides has been realized by treatment with Lawesson reagent. A variety of 5-amino-1,2,3-thiadiazoles containing secondary amines are made in high to excellent yields.</div></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"161 ","pages":"Article 155564"},"PeriodicalIF":1.5000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040403925001133","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Thionation of tertiary α-diazoamides has been realized by treatment with Lawesson reagent. A variety of 5-amino-1,2,3-thiadiazoles containing secondary amines are made in high to excellent yields.
期刊介绍：
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
