Structural Design of Biodegradable Mg Gastrointestinal Anastomosis Staples for Corrosion and Mechanical Strength Analysis.

Abstract

Magnesium (Mg) and its alloys, as next-generation materials for anastomosis staples, offer promising advantages such as biodegradability, biocompatibility, and reduced risk of long-term complications compared to traditional titanium materials. However, the performance of biodegradable staples is highly dependent on their structure. In this study, a biodegradable high-purity (HP) Mg staple with an optimized structure intended for small intestine anastomosis was developed and evaluated in vitro. The designed staple, with a diameter of 0.3 mm, featured an interior angle of 100° and a height of 3.8 mm. This design exhibited a maximum effective stress of approximately 170 MPa and an effective strain of 1.63. The staple could maintain structural integrity without fracture after 7 days of in vitro corrosion testing and exhibited a relatively high burst pressure of approximately 54.70 ± 2.51 mmHg. These findings indicate that the newly designed HP Mg staple combines superior corrosion resistance and anastomosis strength, confirming its potential for clinical application.