The Role of 4D Flow MRI-derived Wall Shear Stress in Aortic Disease: A Comprehensive Review.

IF 1.3 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Reviews in cardiovascular medicine Pub Date : 2025-03-05 eCollection Date: 2025-03-01 DOI:10.31083/RCM26735
Ying Liu, Xiaolin Mu, Yixin Wang, Zhe Xu, Yang Song
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Abstract

Aortic diseases, such as aortic dissection and aortic rupture, often lead to catastrophic complications, significantly increasing morbidity and mortality. Population-based screening for early detection in asymptomatic individuals is not feasible due to high costs and practical challenges. However, recent advancements in four dimensions (4D) Flow magnetic resonance imaging (MRI) offer a comprehensive tool for evaluating hemodynamic changes within the aortic lumen. This technology allows for the quantification and visualization of flow patterns and the calculation of advanced hemodynamic parameters, such as wall shear stress (WSS). WSS is crucial in the development, risk stratification, and surgical outcomes of aortic diseases and their complications, enabling noninvasive and quantitative screening of high-risk populations. This review explores the current status and limitations of 4D flow MRI-derived WSS imaging for aortic disease.

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4D血流mri衍生的壁剪切应力在主动脉疾病中的作用:全面回顾。
主动脉疾病,如主动脉夹层和主动脉破裂,往往导致灾难性的并发症,显著增加发病率和死亡率。由于高成本和实际挑战,在无症状个体中进行基于人群的早期发现筛查是不可行的。然而,最近在四维(4D)血流磁共振成像(MRI)方面的进展为评估主动脉腔内血流动力学变化提供了一个全面的工具。该技术可以量化和可视化流动模式,并计算先进的血流动力学参数,如壁面剪切应力(WSS)。WSS在主动脉疾病及其并发症的发展、风险分层和手术结果中至关重要,可以对高危人群进行无创和定量筛查。本文综述了主动脉疾病的四维血流mri衍生WSS成像的现状和局限性。
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来源期刊
Reviews in cardiovascular medicine
Reviews in cardiovascular medicine 医学-心血管系统
CiteScore
2.70
自引率
3.70%
发文量
377
审稿时长
1 months
期刊介绍: RCM is an international, peer-reviewed, open access journal. RCM publishes research articles, review papers and short communications on cardiovascular medicine as well as research on cardiovascular disease. We aim to provide a forum for publishing papers which explore the pathogenesis and promote the progression of cardiac and vascular diseases. We also seek to establish an interdisciplinary platform, focusing on translational issues, to facilitate the advancement of research, clinical treatment and diagnostic procedures. Heart surgery, cardiovascular imaging, risk factors and various clinical cardiac & vascular research will be considered.
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