Initial experience with ultrafine choledochoscopy combined with low-dose atropine for the treatment of Oddi intersphincter stones.

IF 1.7 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY World Journal of Gastrointestinal Surgery Pub Date : 2025-03-27 DOI:10.4240/wjgs.v17.i3.102998
Xiao-Si Hu, Yong Wang, Hong-Tao Pan, Chao Zhu, Shuai Zhou, Shi-Lei Chen, Hui-Chun Liu, Qing Pang, Hao Jin
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Abstract

Background: In recent years, the use of ultrafine choledochoscopy has gradually increased in the treatment of cholelithiasis. However, stone incarceration and residual spasm of the sphincter of Oddi may be inevitable when an ultrafine choledochoscope is used alone.

Aim: To investigate the safety and feasibility of ultrafine choledochoscopy combined with low-dose atropine in the treatment of Oddi intersphincter stones.

Methods: Seventeen patients with Oddi intersphincter stones were retrospectively analyzed. The perioperative clinical data and follow-up information were collected.

Results: Among the 17 patients, 3 were male and 14 were female. The mean age was 40.6 ± 13.9 years, and the mean diameter of the common bile duct was 7.8 ± 1.3 mm. All patients successfully underwent Oddi intersphincter stone removal using a combination of ultrafine choledochoscopy and low-dose atropine. No serious complications, such as postoperative hemorrhage, pancreatitis or bile leakage occurred in the 17 patients. During the one-year follow-up, none of the patients experienced stone recurrence.

Conclusion: Ultrafine choledochoscopy combined with low-dose atropine is safe and feasible for the treatment of Oddi intersphincter stones.

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超细胆道镜联合小剂量阿托品治疗Oddi括约肌间结石的初步体会。
背景:近年来,超细胆道镜在胆石症治疗中的应用逐渐增多。然而,单独使用超细胆道镜时,可能不可避免地会出现结石嵌顿和Oddi括约肌残留痉挛。目的:探讨超细胆道镜联合小剂量阿托品治疗Oddi括约肌间结石的安全性和可行性。方法:对17例Oddi括约肌间结石患者进行回顾性分析。收集围手术期临床资料及随访资料。结果:17例患者中,男性3例,女性14例。平均年龄40.6±13.9岁,胆总管平均直径7.8±1.3 mm。所有患者均成功采用超细胆道镜联合低剂量阿托品进行Oddi括约肌间结石取出。17例患者均未出现术后出血、胰腺炎、胆漏等严重并发症。在一年的随访中,没有患者出现结石复发。结论:超细胆道镜联合小剂量阿托品治疗Oddi括约肌间结石安全可行。
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