Nonsurgical treatment of postoperative intestinal obstruction caused by heterotopic ossification of the mesentery: A case report.

IF 1.7 4区 医学 Q3 GASTROENTEROLOGY & HEPATOLOGY World Journal of Gastrointestinal Surgery Pub Date : 2025-03-27 DOI:10.4240/wjgs.v17.i3.99015
Jing-Tian Chen, Yao-Ping Li, Shang-Qi Guo, Jin-Sheng Huang, Yong-Gang Wang
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Abstract

Background: Among all forms of heterotopic ossification, heterotopic mesenteric ossification (HMO) is rare, with fewer than 100 reported cases to date. Postoperative early small bowel obstruction caused by HMO is even rarer, presenting extremely high surgical risks, the potential for multiple surgeries, and a poor prognosis. There have been no reported cases of conservative treatment for resolving such early postoperative obstruction.

Case summary: A 57-year-old male presented with severe postoperative small bowel obstruction shortly after undergoing open radical resection for transverse colon cancer. Laparotomy revealed extensive adhesions in the proximal jejunum and mesentery, making it too difficult to relieve without injuring the small bowel. Additionally, multiple fixed nodules were found in the mesentery during the operation. Pathology confirmed the presence of heterotopic ossification. The patient was treated with methylprednisolone on postoperative day 1, which gradually relieved his symptoms.

Conclusion: Hormone therapy may have a potential role in treating small bowel obstruction caused by early HMO after operative intervention.

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肠系膜异位骨化所致术后肠梗阻的非手术治疗1例。
背景:在所有异位骨化形式中,异位肠系膜骨化(HMO)是罕见的,迄今为止报道的病例不到100例。术后早期由HMO引起的小肠梗阻更为罕见,手术风险极高,可能需要多次手术,预后较差。目前尚无保守治疗解决此类术后早期梗阻的病例报道。病例总结:一名57岁男性在横断面结肠癌行开放性根治术后不久出现严重的术后小肠梗阻。剖腹探查发现空肠近端和肠系膜有广泛粘连,很难在不损伤小肠的情况下解除粘连。此外,术中发现肠系膜内多发固定结节。病理证实存在异位骨化。术后第1天给予甲强的松龙治疗,症状逐渐缓解。结论:激素治疗对早期HMO术后小肠梗阻有潜在的治疗作用。
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