Operational Improvement of a Proton Therapy System From Reduced Energy Layer Switching Time.

IF 2 Q3 ONCOLOGY International Journal of Particle Therapy Pub Date : 2025-02-25 eCollection Date: 2025-06-01 DOI:10.1016/j.ijpt.2025.100742
Mark E Artz, Hardev S Grewal, Yawei Zhang, Perry B Johnson, Mohammad Saki, Niek Schreuder, Eric D Brooks, Jiyeon Park
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Abstract

Purpose: This study reports the potential operational improvement provided by reduced energy layer switching time and total beam delivery time of a 3-room IBA ProteusPLUS system.

Materials and methods: Eight treatment fields, including various disease sites and a reference cube, were analyzed for energy layer switching time and total delivery time before and after an energy layer switching time upgrade. The upgraded beam delivery time estimated the total treatment capacity for a 12-h treatment day using a 3-room system with a single common cyclotron. The potential increase in revenue was estimated using Medicare reimbursement rates for proton therapy intermediate.

Results: The average layer switching time was reduced from 6.33 to 1.86 s, reducing the average field delivery time from 240 to 113 s. Overall, the average energy layer switching time reduction was 70.6%, and the average total treatment field delivery time was reduced by 52.6%. Head and neck cancer fields experienced the greatest treatment time reduction of 59.5%, reducing from 236 to 95.5 s. The treatment field delivery time reduction allowed an increase from 60 to 127 patients per day, an increase of 112%.

Conclusion: Reductions in energy layer switching time significantly decreased treatment field delivery time. Reduced treatment field delivery time may provide clinical benefits to patients through improved patient alignment and comfort. Increased treatment capacity could also improve patient access to proton therapy for disease sites that may experience clinical benefits, such as head and neck cancer.

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从减少能量层转换时间改进质子治疗系统的操作。
目的:本研究报告了三室IBA ProteusPLUS系统减少能量层切换时间和总光束传输时间所提供的潜在操作改进。材料与方法:分析了8个治疗领域,包括不同的疾病部位和一个参考立方体,能量层切换时间和能量层切换时间升级前后的总递送时间。升级后的光束输送时间估计了使用带有单个公共回旋加速器的3室系统的12小时处理日的总处理能力。使用质子治疗中间体的医疗保险报销率来估计收入的潜在增加。结果:平均层间切换时间从6.33 s减少到1.86 s,平均现场投递时间从240 s减少到113 s。总体而言,平均能量层切换时间减少了70.6%,平均总处理场交付时间减少了52.6%。头颈部癌症领域的治疗时间减少最多,从236秒减少到95.5秒,减少了59.5%。治疗现场递送时间的减少使每天的患者数量从60人增加到127人,增加了112%。结论:能量层切换时间的减少显著缩短了治疗场递送时间。减少治疗现场递送时间可以通过改善患者对齐和舒适度为患者提供临床益处。治疗能力的提高还可以改善患者对可能具有临床益处的疾病部位(如头颈癌)进行质子治疗的机会。
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来源期刊
International Journal of Particle Therapy
International Journal of Particle Therapy Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
3.70
自引率
5.90%
发文量
23
审稿时长
20 weeks
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