Insufficient weight loss after bariatric surgery and its predictors: Tehran Obesity Treatment Study (TOTS).

IF 1.8 3区医学 Q2 SURGERY Langenbeck's Archives of Surgery Pub Date : 2025-04-02 DOI:10.1007/s00423-025-03682-z

Minoo Heidari Almasi, Maryam Barzin, Maryam Mahdavi, Alireza Khalaj, Danial Ebrahimi, Majid Valizadeh, Farhad Hosseinpanah

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Abstract

Background: This study aimed to determine the factors related to insufficient weight loss (IWL) following bariatric surgery.

Methods: The data for 3456 individuals who had bariatric surgery were obtained prospectively. A bioelectrical impedance analyzer was used to measure body composition changes and compare them between the sufficient (SWL) and IWL groups. The generalized estimated equation approach was used to assess changes in fat mass (FM), fat-free mass (FFM), FFM loss/weight loss percentage (FFML/WL%), and excess weight loss percentage (EWL%). Multivariate logistic regression models were used for IWL to establish independent baseline factors.

Results: IWL was recorded in 8% of the cases. The data analysis revealed substantial differences in the changes in FM%, FFM%, FFML/WL%, and EWL% between the SWL and IWL groups after six months of follow-up. The IWL group demonstrated a greater FFML/WL% (Ptime before & after 6 months < 0.05). An older age, a higher baseline BMI, diabetes mellitus (DM), non-smoking, and sleeve gastrectomy (SG) were the predictors of IWL.

Conclusion: the significant predictors of IWL included older age, a higher baseline BMI, DM, SG, and non-smoking.

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减肥手术后体重减轻不足及其预测因素：德黑兰肥胖治疗研究（TOTS）。

背景：本研究旨在确定减肥手术后体重减轻不足（IWL）的相关因素。方法：对3456例接受减肥手术的患者进行前瞻性数据分析。用生物电阻抗分析仪测量足量（SWL）组和IWL组的体成分变化并进行比较。采用广义估计方程法评估脂肪质量（FM）、无脂质量（FFM）、FFM减重/减重百分比（FFML/WL%）和超重减重百分比（EWL%）的变化。IWL采用多变量logistic回归模型建立独立的基线因素。结果：IWL发生率为8%。数据分析显示，经过6个月的随访，SWL组和IWL组之间FM%、FFM%、FFML/WL%和EWL%的变化存在显著差异。IWL组的FFML/WL%（6个月前和6个月后的Ptime）更高。结论：IWL的重要预测因素包括年龄较大、基线BMI、DM、SG和不吸烟。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Langenbeck's Archives of Surgery 医学-外科

CiteScore

3.30

自引率

8.70%

发文量

342

审稿时长

4-8 weeks

期刊介绍： Langenbeck''s Archives of Surgery aims to publish the best results in the field of clinical surgery and basic surgical research. The main focus is on providing the highest level of clinical research and clinically relevant basic research. The journal, published exclusively in English, will provide an international discussion forum for the controlled results of clinical surgery. The majority of published contributions will be original articles reporting on clinical data from general and visceral surgery, while endocrine surgery will also be covered. Papers on basic surgical principles from the fields of traumatology, vascular and thoracic surgery are also welcome. Evidence-based medicine is an important criterion for the acceptance of papers.