{"title":"Breast cancer metastasis to the reproductive system: Report of 2 cases and literature review: A case report.","authors":"Hailing Liao, Xiaorong Hou, Xiaoyan Chang","doi":"10.3892/mco.2025.2839","DOIUrl":null,"url":null,"abstract":"<p><p>Metastatic involvement of the reproductive system in patients with breast cancer is rare and has been reported only a few times in the literature. Notably, among patients without clinical symptoms, reproductive system metastases are easily overlooked and difficult to distinguish from primary tumors of the reproductive system, especially when the patient is receiving endocrine therapy. The prognosis of breast cancer is better than that of other aggressive cancers. However, if distant metastasis occurs, survival decreases greatly. In the present study, 2 cases of reproductive system metastasis from breast cancer were reported and the relevant literature was reviewed to provide support for the accurate diagnosis and appropriate treatment of affected patients.</p>","PeriodicalId":18737,"journal":{"name":"Molecular and clinical oncology","volume":"22 5","pages":"44"},"PeriodicalIF":1.4000,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959219/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular and clinical oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3892/mco.2025.2839","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Metastatic involvement of the reproductive system in patients with breast cancer is rare and has been reported only a few times in the literature. Notably, among patients without clinical symptoms, reproductive system metastases are easily overlooked and difficult to distinguish from primary tumors of the reproductive system, especially when the patient is receiving endocrine therapy. The prognosis of breast cancer is better than that of other aggressive cancers. However, if distant metastasis occurs, survival decreases greatly. In the present study, 2 cases of reproductive system metastasis from breast cancer were reported and the relevant literature was reviewed to provide support for the accurate diagnosis and appropriate treatment of affected patients.