Fe3+-mediated selective 1,2-Se (S) bifunctionalization of olefin†

IF 2.7 3区 化学 Q1 CHEMISTRY, ORGANIC Organic & Biomolecular Chemistry Pub Date : 2025-03-24 Epub Date: 2025-03-31 DOI:10.1039/d5ob00248f
Hong Yang , Gao-wen Ren , Zhang-gao Le , Zong-bo Xie
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Abstract

A one-pot, four-component reaction for simultaneously constructing C–Se, C–S, and C–N bonds via iron-mediated olefin 1,2-bifunctionalization was described. β-Selenylethyl dithiocarbamates were obtained highly efficiently with a wide substrate scope and remarkable regioselectivity. Notably, non-activated olefins exhibit higher reactivity in this reaction system, achieving yields of up to 99%.

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Fe3+介导的选择性1,2- se (S)双官能化烯烃。
该研究描述了一种通过铁介导的烯烃 1,2 双官能化同时构建 C-Se、C-S 和 C-N 键的一锅四组分反应。β-硒乙基二硫代氨基甲酸酯的获得效率高、底物范围广且具有显著的区域选择性。值得注意的是,非活化烯烃在该反应体系中表现出更高的反应活性,产率高达 99%。
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来源期刊
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry 化学-有机化学
CiteScore
5.50
自引率
9.40%
发文量
1056
审稿时长
1.3 months
期刊介绍: Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.
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