Seizures caused by a solitary fibrous tumour of the pleura: an unusual presentation of Doege-Potter syndrome.

Abstract

Doege-Potter syndrome (DPS) is a rare condition that causes hypoinsulinaemic hypoglycaemia due to solitary fibrous tumours (SFTs). This case report details the treatment of a man in middle adulthood (ages 40-65) diagnosed with DPS after experiencing syncope and vasovagal episodes, which led to the discovery of a large mass in the pleura. Following various diagnostic tests confirming the SFT, the patient required anticonvulsant therapy and glucose infusions due to recurrent seizures and severe hypoglycaemia prior to surgery. After the surgical removal of the tumour, both hypoglycaemia and the need for anticonvulsants were resolved. This case highlights the importance of considering DPS in patients with unexplained hypoglycaemia and intrathoracic masses. It concludes that surgical resection is the preferred treatment for SFTs associated with DPS, offering a favourable prognosis, and emphasises the need for regular follow-up to monitor for potential recurrence.