Comparing Cardiovascular Mortality Estimates From Global Burden of Disease and From the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research.

IF 6.7 2区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Circulation-Cardiovascular Quality and Outcomes Pub Date : 2025-05-01 Epub Date: 2025-04-04 DOI:10.1161/CIRCOUTCOMES.124.011459

Abdul Mannan Khan Minhas, Sadeer Al-Kindi, Harriette G C Van Spall, Dmitry Abramov

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Abstract

Background: Several sources of data, including the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research (CDC WONDER) and the Global Burden of Disease (GBD) data set, report causes of mortality in the United States. While CDC WONDER contains data based on death certificate codes, the GBD mortality data undergo additional processing, such as cause-of-death reassignment before reporting. Potential differences in reported mortality from cardiovascular disease in the United States between these 2 data sources have not been characterized.

Methods: US nationwide cardiovascular cause-of-death data for each year between 2000 and 2019 were obtained from the GBD and the Multiple Cause-of-Death files using CDC WONDER in this longitudinal study. In addition to mortality from cardiovascular disease, mortality from key components of cardiovascular disease, including ischemic heart disease, stroke, and atrial fibrillation/flutter, was determined from each data set. Absolute and crude mortality rates per 100 000 are reported for each data set. Percent differences in cardiovascular mortality from GBD and CDC WONDER and percent changes in cardiovascular mortality across years were calculated.

Results: In 2019, GBD reported 957 455 (95% uncertainty interval, 855 065-1 013 175) cardiovascular deaths, while CDC WONDER reported 859 290 cardiovascular deaths in the United States. Between 2000 and 2019, the reported crude mortality rates from cardiovascular causes in GBD decreased from 327 (297-341) to 292 (261-309), a reduction of 10.7%, and decreased in CDC WONDER from 335 (334-335) to 267 (266-267), a reduction of 20.3%. In 2019, the reported mortality rates for components of cardiovascular disease were higher in GBD compared with CDC WONDER for ischemic heart disease (percent difference, 54.5%), stroke (percent difference, 26.1%), and atrial fibrillation/flutter (percent difference, 25.0%).

Conclusions: There are prominent differences in reported cardiovascular mortality between GBD and CDC WONDER data.

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比较《全球疾病负担》和美国疾病控制和预防中心用于流行病学研究的广泛在线数据对心血管疾病死亡率的估计。

背景：几个数据来源，包括疾病控制和预防中心广泛的流行病学研究在线数据（CDC WONDER）和全球疾病负担（GBD）数据集，报告了美国的死亡原因。虽然CDC WONDER包含基于死亡证明代码的数据，但GBD死亡率数据经过额外处理，例如在报告前重新分配死因。在美国，这两个数据来源之间报告的心血管疾病死亡率的潜在差异尚未得到表征。方法：在这项纵向研究中，使用CDC WONDER从GBD和多死因文件中获取2000年至2019年每年美国全国心血管死因数据。除了心血管疾病的死亡率外，还从每个数据集中确定了心血管疾病的关键组成部分（包括缺血性心脏病、中风和心房颤动/扑动）的死亡率。报告了每10万人的绝对死亡率和粗死亡率。计算GBD和CDC WONDER的心血管死亡率的百分比差异以及心血管死亡率的变化百分比。结果：2019年，GBD报告了957 455例（95%不确定区间，855 065-1 013 175）心血管死亡，而CDC WONDER报告了859 290例心血管死亡。在2000年至2019年期间，GBD中报告的心血管原因的粗死亡率从327（297-341）下降到292(261-309)，减少了10.7%，CDC WONDER从335（334-335）下降到267(266-267)，减少了20.3%。2019年，与CDC WONDER相比，GBD中心血管疾病组成部分的死亡率在缺血性心脏病（百分比差异，54.5%）、中风（百分比差异，26.1%）和心房颤动/扑动（百分比差异，25.0%）中高于CDC WONDER。结论：GBD报告的心血管死亡率与CDC WONDER数据存在显著差异。

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来源期刊

Circulation-Cardiovascular Quality and Outcomes CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

8.50

自引率

2.90%

发文量

357

审稿时长

4-8 weeks

期刊介绍： Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal, publishes articles related to improving cardiovascular health and health care. Content includes original research, reviews, and case studies relevant to clinical decision-making and healthcare policy. The online-only journal is dedicated to furthering the mission of promoting safe, effective, efficient, equitable, timely, and patient-centered care. Through its articles and contributions, the journal equips you with the knowledge you need to improve clinical care and population health, and allows you to engage in scholarly activities of consequence to the health of the public. Circulation: Cardiovascular Quality and Outcomes considers the following types of articles: Original Research Articles, Data Reports, Methods Papers, Cardiovascular Perspectives, Care Innovations, Novel Statistical Methods, Policy Briefs, Data Visualizations, and Caregiver or Patient Viewpoints.