Amanda Alves da Cruz, Gustavo Henrique Couto, Cristiane Pilissão
{"title":"Antibacterial properties of nanocomposites based on titanate nanotubes and bacterial nanocellulose functionalized through UGI reaction","authors":"Amanda Alves da Cruz, Gustavo Henrique Couto, Cristiane Pilissão","doi":"10.1007/s10570-025-06431-z","DOIUrl":null,"url":null,"abstract":"<div><p>Globally, there is a significant concern about controlling the growth of pathogenic microorganisms to prevent infectious diseases. In this context, the study focused on the synthesis of a nanocomposite via the Ugi multicomponent reaction using silanized titanate nanotubes [NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub>] and bacterial nanocellulose (BNC–COOH) with antimicrobial properties. The NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub> exhibited antimicrobial activity, with inhibition halos of 21 mm against <i>S. aureus</i> and 25 mm against <i>E. coli</i>. Additionally, the [BNC–COOH/NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub>] nanocomposite was tested against Gram-negative and Gram-positive bacteria, showing inhibition halos of 9 mm against <i>E. coli</i> and 15 mm against <i>S. aureus</i>, indicating sensitivity comparable to that of chloramphenicol.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":511,"journal":{"name":"Cellulose","volume":"32 5","pages":"3095 - 3112"},"PeriodicalIF":4.8000,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cellulose","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s10570-025-06431-z","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, PAPER & WOOD","Score":null,"Total":0}
引用次数: 0
Abstract
Globally, there is a significant concern about controlling the growth of pathogenic microorganisms to prevent infectious diseases. In this context, the study focused on the synthesis of a nanocomposite via the Ugi multicomponent reaction using silanized titanate nanotubes [NtsTi–Si(CH2)3NH2] and bacterial nanocellulose (BNC–COOH) with antimicrobial properties. The NtsTi–Si(CH2)3NH2 exhibited antimicrobial activity, with inhibition halos of 21 mm against S. aureus and 25 mm against E. coli. Additionally, the [BNC–COOH/NtsTi–Si(CH2)3NH2] nanocomposite was tested against Gram-negative and Gram-positive bacteria, showing inhibition halos of 9 mm against E. coli and 15 mm against S. aureus, indicating sensitivity comparable to that of chloramphenicol.
期刊介绍：
Cellulose is an international journal devoted to the dissemination of research and scientific and technological progress in the field of cellulose and related naturally occurring polymers. The journal is concerned with the pure and applied science of cellulose and related materials, and also with the development of relevant new technologies. This includes the chemistry, biochemistry, physics and materials science of cellulose and its sources, including wood and other biomass resources, and their derivatives. Coverage extends to the conversion of these polymers and resources into manufactured goods, such as pulp, paper, textiles, and manufactured as well natural fibers, and to the chemistry of materials used in their processing. Cellulose publishes review articles, research papers, and technical notes.
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