Interpenetrating Polymer Network Hydrogels with Tunable Viscoelasticity and Proteolytic Cleavability to Direct Stem Cells In Vitro (Adv. Healthcare Mater. 9/2025)
Prannoy Seth, Jens Friedrichs, Yanuar Dwi Putra Limasale, Nicole Fertala, Uwe Freudenberg, Yixin Zhang, Ayala Lampel, Carsten Werner
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引用次数: 0
Abstract
Viscoelastic sGAG-Hydrogels
In article 2402656, Carsten Werner and co-workers introduce a sulfated glycosaminoglycan (sGAG)-based interpenetrating polymer network hydrogel platform with tunable viscoelasticity, stiffness, and proteolytic cleavability. This platform enables the detailed study of stem cell morphogenesis, showing improved cell spreading and YAP activation in human mesenchymal stem cells, and modified morphogenesis in human induced pluripotent stem cell cysts.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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