Guangyu Cui, Zaiqi Han, Xiangqing Feng, Haifeng Du
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引用次数: 0
Abstract
An enantioselective synthesis of 2-aryl 3,3-disubstituted 3H-indoles has been successfully developed via a deracemization process involving borane-catalyzed hydrogenation and chiral phosphoric-acid-catalyzed asymmetric transfer hydrogenation. A variety of 3H-indoles were effective substrates to afford the desired indolines in 86–95% yields with 45–92% ee’s.
期刊介绍：
Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.
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