Enhanced thyroid nodule detection and diagnosis: a mobile-optimized DeepLabV3+ approach for clinical deployments.

IF 3.2 3区 医学 Q2 PHYSIOLOGY Frontiers in Physiology Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI:10.3389/fphys.2025.1457197
Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu
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Abstract

Objective: This study aims to enhance the efficiency and accuracy of thyroid nodule segmentation in ultrasound images, ultimately improving nodule detection and diagnosis. For clinical deployment on mobile and embedded devices, DeepLabV3+ strives to achieve a balance between a lightweight architecture and high segmentation accuracy.

Methodology: A comprehensive dataset of ultrasound images was meticulously curated using a high-resolution ultrasound imaging device. Data acquisition adhered to standardized protocols to ensure high-quality imaging. Preprocessing steps, including noise reduction and contrast optimization, were applied to enhance image clarity. Expert radiologists provided ground truth labels through meticulous annotation. To improve segmentation performance, we integrated MobileNetV2 and Depthwise Separable Dilated Convolution into the Atrous Spatial Pyramid Pooling (ASPP) module, incorporating the Pyramid Pooling Module (PPM) and attention mechanisms. To mitigate classification imbalances, we employed Tversky loss functions in the ultrasound image classification process.

Results: In semantic image segmentation, DeepLabV3+ achieved an impressive Intersection over Union (IoU) of 94.37%, while utilizing only 12.4 MB of parameters, including weights and biases. This remarkable accuracy demonstrates the effectiveness of our approach. A high IoU value in medical imaging analysis reflects the model's ability to accurately delineate object boundaries.

Conclusion: DeepLabV3+ represents a significant advancement in thyroid nodule segmentation, particularly for thyroid cancer screening and diagnosis. The obtained segmentation results suggest promising directions for future research, especially in the early detection of thyroid nodules. Deploying this algorithm on mobile devices offers a practical solution for early diagnosis and is likely to improve patient outcomes.

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增强甲状腺结节检测和诊断:用于临床部署的移动优化DeepLabV3+方法。
目的:本研究旨在提高超声图像中甲状腺结节分割的效率和准确性,最终提高结节的检测和诊断水平。对于在移动和嵌入式设备上的临床部署,DeepLabV3+努力实现轻量级架构和高分割精度之间的平衡。方法:使用高分辨率超声成像设备精心策划了超声图像的综合数据集。数据采集遵循标准化方案,确保高质量成像。预处理步骤包括降噪和对比度优化,以提高图像清晰度。放射科专家通过细致的注释提供了地面真相标签。为了提高分割性能,我们将MobileNetV2和深度可分离扩展卷积集成到空间金字塔池(ASPP)模块中,并结合金字塔池模块(PPM)和注意机制。为了减轻分类不平衡,我们在超声图像分类过程中采用了Tversky损失函数。结果:在语义图像分割中,DeepLabV3+仅利用12.4 MB的参数(包括权重和偏置),实现了令人印象深刻的94.37%的交集超过联合(IoU)。这种惊人的准确性证明了我们方法的有效性。医学成像分析中的高IoU值反映了该模型准确描绘物体边界的能力。结论:DeepLabV3+在甲状腺结节分割方面取得了重大进展,特别是在甲状腺癌的筛查和诊断方面。所获得的分割结果为未来的研究提供了有希望的方向,特别是在甲状腺结节的早期发现方面。在移动设备上部署这种算法为早期诊断提供了一种实用的解决方案,并有可能改善患者的治疗效果。
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来源期刊
CiteScore
6.50
自引率
5.00%
发文量
2608
审稿时长
14 weeks
期刊介绍: Frontiers in Physiology is a leading journal in its field, publishing rigorously peer-reviewed research on the physiology of living systems, from the subcellular and molecular domains to the intact organism, and its interaction with the environment. Field Chief Editor George E. Billman at the Ohio State University Columbus is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
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