Nissen fundoplication in patients with gastroesophageal reflux disease and ineffective esophageal motility.

IF 4 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Revista Espanola De Enfermedades Digestivas Pub Date : 2025-04-08 DOI:10.17235/reed.2025.11218/2025
Luis Candil Valero, José Ruiz Pardo, Pedro Antonio Sánchez Fuentes, Elisabet Vidaña Márquez, Ana María Fuentes Zaplana, Ricardo Belda Lozano, Javier Martín Cano, Ángel Reina Duarte
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Abstract

In patients with gastroesophageal reflux disease (GERD) and ineffective esophageal motility (IEM) who have surgical indication, there is controversy regarding the fundoplication to be performed, since Nissen fundoplication (NF) could increase the risk of postoperative dysphagia. Furthermore, studies that have evaluated NF for the treatment of GERD in patients with IEM are scarce. The aim of this study is to analyze the results of NF in patients with GERD and IEM. A retrospective study is carried out, whose study population consisted of patients with GERD and IEM who underwent NF between 2017 and 2023. Patients younger than 18 years, with paraesophageal hernias (II-IV), reinterventions and those with a follow-up of less than one year are excluded. Twenty-seven patients met the selection criteria. There were no complications (infection, bleeding or perforation), reinterventions or readmissions during the first 30 postoperative days. Moreover, 22,2% (n=6) had self-limited dysphagia that resolved in less than 3 months and 14,8% (n=4) had gas-bloat syndrome that resolved in the first 6 months. After 6 months, 18,5% (n=5) of the patients presented some degree of dysphagia, whose causes were: hiatal hernia in 3 cases, stenosis of the NF in one case and functional in another case. NF stenosis was resolved with endoscopic dilatations. After a mean follow-up of 53,1 ± 22,8 months, 22,2% (n=6) presented recurrence of GERD.

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胃食管反流病和食管运动不良患者的尼森底重复。
对于有手术指征的胃食管反流病(GERD)和食管动力不良(IEM)患者,由于Nissen底翻术(NF)会增加术后吞咽困难的风险,因此对是否进行底翻术存在争议。此外,评估NF治疗IEM患者胃食管反流的研究很少。本研究的目的是分析NF在GERD和IEM患者中的结果。进行了一项回顾性研究,其研究人群包括2017年至2023年间接受NF治疗的GERD和IEM患者。排除年龄小于18岁、食管旁疝(II-IV)、再干预和随访时间少于1年的患者。27例患者符合入选标准。术后30天无并发症(感染、出血或穿孔)、再干预或再入院。此外,22.2% (n=6)的自限性吞咽困难在不到3个月的时间内消退,14.8% (n=4)的气胀综合征在前6个月消退。6个月后,18.5% (n=5)的患者出现不同程度的吞咽困难,其原因为:裂孔疝3例,NF狭窄1例,功能性1例。内窥镜扩张解决了NF狭窄。平均随访53,1±22,8个月后,22.2% (n=6)出现返流性胃食管反流。
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来源期刊
CiteScore
2.00
自引率
25.00%
发文量
400
审稿时长
6-12 weeks
期刊介绍: La Revista Española de Enfermedades Digestivas, Órgano Oficial de la Sociedad Española de Patología Digestiva (SEPD), Sociedad Española de Endoscopia Digestiva (SEED) y Asociación Española de Ecografía Digestiva (AEED), publica artículos originales, editoriales, revisiones, casos clínicos, cartas al director, imágenes en patología digestiva, y otros artículos especiales sobre todos los aspectos relativos a las enfermedades digestivas.
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