Single-Center, Open-Label Study Study to Evaluate Improvement of Hair Appearance With Novel Hair Growth Serum.

Abstract

Background: REVIVV® is a topical hair growth serum with a proprietary formula of botanicals that addresses multiple factors involved in hair loss pathophysiology. This open-label, prospective, single-center study evaluated the efficacy of REVIVV®, a topical hair growth serum, in 20 adults (10 male, 10 female) with mild to moderate hair loss over 6 months. Participants applied the serum twice daily, and assessments were conducted at baseline, 4, 12, and 24 weeks. Dermatologist evaluations and patient self-assessments of hair quality and growth were performed using a 7-point Likert scale. Results Investigator-rated improvements in hair quality and growth increased from 0.75 and 0.81 at 4 weeks to 1.73 and 1.83 at 24 weeks, respectively. Patient-reported assessments showed that 85% of participants noted improved hair quality and growth at 24 weeks, with 50% reporting great improvement. Patient satisfaction was high, with 80% of participants being moderately or greatly satisfied at 4 weeks, increasing to 95% at 24 weeks. No adverse events related to the serum were reported throughout the study. The results demonstrate that twice-daily application of REVIVV®  over 6 months is associated with increased hair growth and improved hair quality suggesting that REVIVV®  may be an effective, non-pharmacological option for individuals seeking to improve hair growth and quality. J Drugs Dermatol. 2025;24(4):394-396. doi:10.36849/JDD.8606 .